Results 81 to 90 of about 1,519,760 (306)

Mobile learning: a meta-ethical taxonomy

open access: yes, 2011
In this paper I discuss some of the ethical issues relating to the use of mobile technologies in education. I argue that the frames of reference used by educators and technologists fail to capture the nature, scope and impact of ethical issues in mobile
Farrow, Robert
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Anthropological and ethical foundations of organization theory [PDF]

open access: yes
The ever more frequent and forceful criticisms of management sciences suggest that we need a new model. In fact, the number of proposed alternatives has multiplied, with some suggesting that the range of economic points of departure be extended, while ...
Argandoña, Antonio
core  

Intending to be ethical: An examination of consumer choice in sweatshop avoidance [PDF]

open access: yes, 2007
While much research in ethical consumption has focused on contexts such as food, this research explores ethical consumer decision-making in the context of intention to avoid sweatshop apparel.
Bekin, C   +4 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Profesionalismo en enfermería, el hábito de la excelencia del cuidado Profissionalismo em enfermagem, o hábito da excelência do cuidado Professionalism in nursing, the habit of excellence in health care

open access: yesAvances en Enfermería, 2010
Enfermería precisa un cambio cualitativo en la práctica profesional, por ello se sugiere transitar de la profesionalización al profesionalismo en enfermería como camino para alcanzar la excelencia profesional y la calidad en el cuidado.
MITZI LETELIER VALDIVIA   +1 more
doaj  

Dilema Etis Profesi Akuntan Berdasarkan Aspek Keperilakuan

open access: yesJurnal Inovasi Akuntansi
The article discusses ethical dilemmas in the accounting profession, focusing on behavioral aspects. The paper highlights the importance of ethics as a foundational component for responsible societies and sustainable development, especially within ...
Nyoman Yudha Astriayu Widyari   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

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