Results 111 to 120 of about 7,899,887 (331)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Discussão Ética sobre o Prontuário Eletrônico do Paciente

Revista Brasileira de Educação Médica
RESUMO O prontuário do paciente constitui uma ferramenta fundamental para a prestação do cuidado em saúde, podendo ser definido como um registro padronizado e organizado de toda a informação referente à saúde de um indivíduo, desde o nascimento até a ...
Maria José Guedes Gondim Almeida, Bárbara Barros Figueiredo, Hakayna Calegaro Salgado, Igor Moreira Torturella   +3 more
doaj   +1 more source

Development of Strategies for Advancement of Medical Ethics Education in Isfahan University of Medical Sciences [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2013
Introduction: Medical ethics is an analytical attempt that deals with various aspects of ethical decision making in medicine. According to the importance and goals of medical ethics, this study is an endeavor to evaluate strengths and weaknesses ...
Parisa Malekahmadi, Parinaz parsa
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Código de ética do estudante de medicina: uma análise qualitativa

Revista Bioética
Este trabalho objetivou comparar os códigos de ética do estudante de medicina existentes no Brasil. Tratou-se de um estudo com abordagem qualitativa utilizando o Código de Ética Médica e o Código de Ética do Estudante de Medicina do Distrito Federal como
Larissa Lisboa, Liliane Lins
doaj  

A Study of the Components of Medical Ethics in Ancient Persian Literature and Its Comparison with Modern Medical Ethics [PDF]

Armaghane Danesh Bimonthly Journal
Background & aim: Findings from ancient Persian literary texts indicate that the issue of professional medical ethics and the correct and logical relationship between a doctor and a patient has not been hidden from the eyes of writers and poets.
A Ebrahimi Mehr
doaj  

Ética e bioética: o que os alunos do sexto ano médico têm a dizer

Revista Brasileira de Educação Médica
A formação ética e bioética é fundamental para a humanização do atendimento preconizada pela política de saúde no Brasil e para o desenvolvimento de um profissional crítico.Estudos recentes revelam que Ética e Bioética têm carga horária restrita nos ...
Aline Camargo, Margareth Aparecida Santini de Almeida, Ione Morita   +2 more
doaj   +1 more source

Progress in Medical Ethics: How the Ethicist Can Help [PDF]

, 1976
In this article Dr. Camenisch presents a plea for mutual understanding between ethicists and medical professionals. He is Associate Professor of Religious Studies at DePaul University and is a post-doctoral Fellow at the Texas Institute of ...
Camenisch, Paul F.
core   +2 more sources

Medical Ethics [PDF]

CA: A Cancer Journal for Clinicians, 1986
H B, Haley, B A, Brody
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source