Results 81 to 90 of about 3,141,195 (309)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Educational Ethics in Academic Environment: Medical Students' Perspectives [PDF]

open access: yes, 2016
Background and Objective: Educational ethics imply values such as honesty, reliance on one's own personal effort, not to abuse the efforts of others, and respect the dignity and respect for others.
Hosseini nejhad, SM.   +4 more
core  

MORALITY, MEDICAL ETHICS AND MEDICAL LAW

open access: yesУкраїнський стоматологічний альманах, 2018
The purpose of the publication of the article is to remind of legal relations between professional health workers and the subject of this relationship (patient), based on the rules of morality and law for patient (health law).
P. I. Yatsenko
doaj  

Ética e bioética: o que os alunos do sexto ano médico têm a dizer

open access: yesRevista Brasileira de Educação Médica
A formação ética e bioética é fundamental para a humanização do atendimento preconizada pela política de saúde no Brasil e para o desenvolvimento de um profissional crítico.Estudos recentes revelam que Ética e Bioética têm carga horária restrita nos ...
Aline Camargo   +2 more
doaj   +1 more source

Advance care planning in Norwegian nursing homes – limited awareness of the residents’ preferences and values? A qualitative study

open access: yesBMC Geriatrics, 2019
Background 52% of all deaths in Norway occur in nursing homes. Still advance care planning (ACP) is scarce and heterogeneous. To improve the implementation and practice of ACP in nursing homes, knowledge about health care professionals’ views on ACP is ...
Lisbeth Thoresen   +4 more
doaj   +1 more source

What is a good health check? An interview study of health check providers’ views and practices

open access: yesBMC Medical Ethics, 2017
Background Health checks identify (risk factors for) disease in people without symptoms. They may be offered by the government through population screenings and by other providers to individual users as ‘personal health checks’.
Yrrah H. Stol   +2 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Protocol for a systematic scoping review of reasons given to justify the performance of randomised controlled trials. [PDF]

open access: yes, 2019
IntroductionRandomised controlled trials (RCTs) are widely viewed to generate the most reliable medical knowledge. However, RCTs are not always scientifically necessary and therefore not always ethical.
Chevrier, Stephanie   +7 more
core   +2 more sources

Development of Strategies for Advancement of Medical Ethics Education in Isfahan University of Medical Sciences [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2013
Introduction: Medical ethics is an analytical attempt that deals with various aspects of ethical decision making in medicine. According to the importance and goals of medical ethics, this study is an endeavor to evaluate strengths and weaknesses ...
Parisa Malekahmadi, Parinaz parsa
doaj  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

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