Results 81 to 90 of about 53,494,435 (296)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Bringing Excitement to Empirical Business Ethics Research: Thoughts on the Future of Business Ethics. [PDF]

J Bus Ethics, 2022
Babalola MT, Bal M, Cho CH, Garcia-Lorenzo L, Guedhami O, Liang H, Shailer G, van Gils S.   +7 more
europepmc   +1 more source

The ESRC's 2010 Framework for Research Ethics: Fit for Research Purpose? [PDF]

The ESRC\'s (2010) Framework for Research Ethics extends the remit of its 2005 research ethics framework in three significant ways: the system is to be fully mandatory and it will no longer possible to make the case that no out of the ordinary ethical ...
Sue Wise, Liz Stanley
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Enabling the Voices of Marginalized Groups of People in Theoretical Business Ethics Research. [PDF]

J Bus Ethics, 2023
Alm K, Guttormsen DSA.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Legibilidade dos termos de consentimento livre e esclarecido em ensaios clínico

Revista Bioética
O estudo objetiva analisar a legibilidade de dois termos de consentimento livre e esclarecido (TCLE) utilizados para participação em ensaio clínico e correlacionar o grau de dificuldade dos documentos com o nível de escolaridade dos participantes.
Lucas Lobato, Beatriz Santana Caçador, Maria Flávia Gazzinelli   +2 more
doaj  

Reasons for resubmission of research projects to the research ethics committee of a University Hospital in São Paulo, Brazil

Clinics, 2009
INTRODUCTION: It is important to know the reasons for resubmitting research projects to the Research Ethics Committee in order to help researchers to prepare their research projects, informed consent forms and needed research documentation.
Mariana Bueno, Maria Meimei Brevidelli, Thaís Cocarelli, Gianni Mara Silva dos Santos, Maria Auxiliadora Ferraz, Décio Mion Jr.   +5 more
doaj   +1 more source

Opening Constructive Dialogues Between Business Ethics Research and the Sociology of Morality: Introduction to the Thematic Symposium. [PDF]

J Bus Ethics, 2021
Shadnam M, Bykov A, Prasad A.
europepmc   +1 more source

MANUAL FOR RESEARCH ETHICS COMMITTEES

, 2003
Editorial board -- Acknowledgements -- List of contributors - - Introduction / Sue Eckstein -- Pt. 1. Section I. Fundamental ethical and legal considerations -- Ch. 1. The ethics of clinical research / Calliope (Bobbie) Farsides -- Ch. 2.
Eckstein, Sue, ed., Centre of Medical Law and Ethics, King's College, London   +1 more
core