Results 81 to 90 of about 2,103,507 (310)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Publicação responsável de pesquisa: padrões internacionais para autores [PDF]

open access: yesCadernos de Pesquisa, 2014
Elizabeth Wager, Sabine Kleinert
doaj   +1 more source

Moral distress, ethical climate, and compassion fatigue among oncology nurses: the mediating role of moral distress

open access: yesBMC Nursing
Background Oncology nurses have a vital role in providing care for individuals with cancer. Ethical dilemmas arise for oncology nurses caring for these patients.
Akbar Zare-Kaseb   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

MINUTE BOOKS OF THE ANIMAL EXPERIMENTATION COMMITTEE / ANIMAL EXPERIMENTATION ETHICS COMMITTEE

open access: yes, 1991
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/71226The
University of Melbourne. Animal Experimentation Ethics Committee
core  

Clinical ethics consultation among Italian ethics committee: A mixed method study.

open access: yesPLoS ONE, 2019
ObjectiveThe general purpose for ethics consultations is to deliberate on issues on medical and scientific research and act towards the safeguard of the patient's rights and dignity.
Ludovica De Panfilis   +5 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Judicial Specific-Purpose Committee Campaign Finance Report

open access: yes, 2014
This is a form for the use of judicial specific-purpose committee campaign finance report issued by the Texas Ethics Commission. Form JSPAC requires information on the committee, contribution totals, loans, expenditures, interest earned, gains, and ...
Texas Ethics Commission
core  

Monthly Filing County Executive Committee Campaign Finance Report: Form MCEC Instruction Guide [PDF]

open access: yes, 2014
Document providing instructions to Form MCEC, a Texas Ethics Commission form for reporting campaign contributions in County Executive Committee ...
Texas Ethics Commission
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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