Results 61 to 70 of about 4,044,090 (301)

Animal Experimentation Ethics Committee B

, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core  

Research Ethics Committees [PDF]

British Journal of General Practice, 2008
Trials and Tribulations by Saul Miller1 takes the National Research Ethics Service to task for the closure of the Northumberland Research Ethics Committee (REC), but there are compelling reasons behind this decision. The Northumberland closure is part …
openaire   +2 more sources

Ethical review key considerations for organoid applications in biomedical research—a systematic review

Frontiers in Cell and Developmental Biology
The organoid co-culture model, a novel tool for reconstructing three-dimensional microenvironments to study cell-cell interactions, has demonstrated significant potential in biomedical research in recent years. It holds considerable value for elucidating
Guo Zhili, Zhang Nenghua
doaj   +1 more source

A survey in Mexico about ethics dumping in clinical research

BMC Medical Ethics, 2019
Background The exportation of unethical practices to low- and middle-income countries (“Ethics Dumping”) has been conceived as a prevalent practice which needs to be examined more closely.
Novoa-Heckel Germán, Bernabe Rosemarie
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Animal Experimentation Ethics Committee A

, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core  

Study protocol to assess clinical outcomes of breast cancer and its relationship with access to healthcare in Brazil—BREAST trial (BRaziLian outcomE for metAStatic breasT cancer): a prospective observational study in HER2-negative/hormone receptor-positive metastatic disease

BMJ Open
Introduction Breast cancer survival rates in low-income and middle-income countries significantly differ from those in high-income countries, indicating limited access to first-line systemic therapy for advanced and metastatic tumours.
Leticia Kawano-Dourado, Alexandre Biasi Cavalcanti, Afonso Celso Pinto Nazário, Vanessa Monteiro Sanvido, Lucíola de Barros Pontes, Rachel HV Machado, Jackeline Oliveira Gomes, Leticia Galvão Barbante, Marina Lazzari Nicola, Samira Martins Tokunaga, Tamiris Abait Miranda, Ligia Nasi Laranjeira, Karina Leal Negrelli, Nanci Valeis, Maria Silvia Petty Moutinho, Henrique Alkalay Helber, Rafael da Silva Sá   +16 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Ethical issues in access to and delivery of emergency department care in an era of changing reimbursement and novel payment models

Journal of the American College of Emergency Physicians Open, 2020
Hospital emergency departments (EDs) and the emergency physicians, nurses, and other health professionals who provide emergency care in them, are a critical component of the United States (US) health care system in the 21st century.
Chadd K. Kraus, John C. Moskop, Kenneth D. Marshall, Kelly Bookman, ACEP Ethics Committee   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source