Results 71 to 80 of about 478,794 (298)

Research ethics paperwork: What is the plot we seem to have lost? [PDF]

open access: yes, 2004
© 2004 BMJ Publishing GroupResearchers in the United Kingdom now have to submit their study proposals to local research ethics committees using a nationally standardised form. The form overcomes the problem of inconsistencies in the paperwork required by
Jamrozik, Konrad
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Research Ethics Committee [PDF]

open access: yesBritish Journal of General Practice, 2007
Once a month does not sound much, but when you see the ream of printed paper that arrives the week before, with a groaning thud on your desk, it feels like a more weighty commitment than it sounds. ‘God’, I mutter to myself. ‘Has another month gone by that quickly?’ For a moment I perceive my life ebbing away in monthly aliquots. With a heavy heart, I
openaire   +1 more source

Més de 25 anys fent camí. Ètica i Treball Social [PDF]

open access: yes, 2011
This article contains the main data from a research study on the ethics and deontology committee of the Association of Social Workers of Catalonia. It describes the history of the committee, some factual information about the consultations addressed to
Alonso, Emilia   +3 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Qualitative health research and procedural ethics: An interview study to investigate researchers’ ways of navigating the demands of medical research ethics committees in Germany

open access: yesResearch Ethics Review
This study explores how qualitative health researchers navigate the demands of medical research ethics committees in Germany where qualitative research is subject to approval only when it is conducted in medical contexts.
Sarah Potthoff   +2 more
doaj   +1 more source

Research ethics committees in Latin America: What do they accomplish?

open access: yesRevista Colombiana de Bioética, 2019
The outsourcing of clinical trials to Latin America began in the mid-1940s under the sponsorship of universities and the National Institutes of Health of the United States of America.
Antonio Ugalde, Nuria Homedes
doaj   +1 more source

Failure to apply for ethical approval for health studies in low-income countries [PDF]

open access: yes, 2015
Too many occasions researchers conduct public health and/or epidemiological studies in low-income countries without the appropriate in-country ethical approval. This article reflects on some of the underlying reasons for not applying for ethical approval.
Simkhada, Padam, van Teijlingen, Edwin
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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