Results 71 to 80 of about 66,392,175 (266)

Bioethics and transdisciplinarity as bridges for dialogue between health sciences and social and/or human sciences in the context of the ethics evaluation of research

Salud Colectiva, 2022
Volnei Garrafa
doaj   +1 more source

Controvérsias sobre a revisão ética de pesquisas em ciências humanas e sociais pelo Sistema CEP/Conep

Revista Bioética
O comitê de ética em pesquisa tem como função revisar todas as pesquisas envolvendo seres humanos realizadas no Brasil, o que tem suscitado controvérsias sobre a revisão ética de pesquisas em ciências humanas e sociais. O objetivo deste artigo é discutir
Adriana Silva Barbosa, Carlos Montero Corrales, Marcos Silbermann   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reforming research ethics committees (Editorial).

, 2005
For the first 25 years of their existence in the United Kingdom research ethics committees were left more or less in peace by the Department of Health. Since the publication of the “red book” in 1991, 1 however, they have undergone a continual process of
Newson, A.J., Benn, PMW, Newson, AJ, Ashcroft, RE   +3 more
core  

BUILDING BIOETHICS CAPACITY IN UKRAINE: THE PARTNERSHIP BETWEEN UKRAINIAN CATHOLIC UNIVERSITY AND LOYOLA UNIVERSITY CHICAGO

Proceedings of the Shevchenko Scientific Society: Medical Sciences
Bioethics remains underdeveloped in Ukraine compared with other European countries. Through a partnership between Ukrainian Catholic University (UCU) in Lviv and Loyola University Chicago (LUC) in Chicago, USA, we have developed bioethics capacity among ...
Emily E. Anderson, Ihor Boyko, Yaryna Pikulytska   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

MANUAL FOR RESEARCH ETHICS COMMITTEES

, 2003
Editorial board -- Acknowledgements -- List of contributors - - Introduction / Sue Eckstein -- Pt. 1. Section I. Fundamental ethical and legal considerations -- Ch. 1. The ethics of clinical research / Calliope (Bobbie) Farsides -- Ch. 2.
Eckstein, Sue, ed., Centre of Medical Law and Ethics, King's College, London   +1 more
core  

Should Research Ethics Committees Be Told How to Think?

, 2007
Research ethics committees (RECs) are charged with providing an opinion on whether research proposals are ethical. These committees are overseen by a central office that acts for the Department of Health and hence the State.
Sayers, G.M.
core   +1 more source

Assessing Perceptions of Research Ethics in Higher Education Institutions in Khyber Pakhtunkhwa-Pakistan

Bioscientific Review
Background. The current study aimed to assess the level of perceptions, attitudes, and awareness regarding research ethics among faculty members and postgraduate students in Higher Education Institutions (HEIs) of Khyber Pakhtunkhwa (KPK), Pakistan ...
Muhammad Ilyas, Shehryar Ahmad, Atta ur Rehman, Muhammad Ayaz, Raza Ullah, Sheraz Ahmad, Muhammad Haroon   +6 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source