Results 81 to 90 of about 860,404 (335)
Ethical challenges in cross-cultural field research: a comparative study of UK and Ghana [PDF]
, 2015 YesResearch ethics review by ethics committees has grown in importance since the end of the Nuremberg trials in 1949. However, ethics committees have come under increasing criticisms either for been ‘toothless or too fierce’ (Fistein & Quilligan, 2012 ...
Adu-Gyamfi, Jones
core +1 more source
Ethics in educational research: review boards, ethical issues and researcher development [PDF]
, 2020 Educational research, and research in the Social Sciences more generally, has experienced a growth in the introduction of ethical review boards since the 1990s.
Head, George
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
BMC Medical Ethics, 2005 Background Clinical trials throughout the world must be evaluated by research ethics committees. No one has yet attempted to clearly quantify at the national level the activity of ethics committees and describe the characteristics of the protocols ...
Lhéritier Véronique +2 more
doaj +1 more source
Failure to apply for ethical approval for health studies in low-income countries [PDF]
, 2015 Too many occasions researchers conduct public health and/or epidemiological studies in low-income countries without the appropriate in-country ethical approval. This article reflects on some of the underlying reasons for not applying for ethical approval.
Simkhada, Padam, van Teijlingen, Edwin
core +1 more source
BMC Medical Ethics, 2017 BackgroundThe conduct of research in settings affected by disasters such as hurricanes, floods and earthquakes is challenging, particularly when infrastructures and resources were already limited pre-disaster.
C. Tansey +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Challenges of Recruiting a Vulnerable Population in a Grounded Theory Study [PDF]
, 2001 Recruitment is a crucial and fundamental part of research and one that poses various degrees of difficulty. This is particularly so when the area of research is one that is either highly sensitive, or that involves participants who are deemed to be ...
Chiang, Vico C +2 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Readability of informed consent documents and its impact on consent refusal rate
Perspectives in Clinical ResearchIntroduction: Informed consent documents (ICDs) are integral to a research project and must provide all required information to the participant. We undertook a 6-year retrospective cross-sectional analysis of ICDs to assess the same. Methods: We accessed
Yash V. Kamath +3 more
doaj +1 more source