Results 91 to 100 of about 166,330,976 (288)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Other title: Guide to the code of ethics

, 2016
Rev. January 2016.; Title from cover.; Previously issued: Guide to the code of ethics for current or potential state contractors.

core   +2 more sources

On the Ethics of War

Kritike: An Online Journal of Philosophy, 2012
One of the most influential and known view regarding the morality of war is the Just War Theory wherein certain requirements must be met in order to justify a war being fought by a state. The traditional Just War Theory judges wars in two principles, the justice of resorting into war in the first place, jus ad bellum and the justice in the conduct of ...
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Welcome to the Ohio Ethics Commission

, 2008
Title from caption of web page (viewed on Apr.
Ohio Ethics Commission.
core  

“Ethics” of war in the SMO soldiers’ letters to children

RUDN journal of Sociology
The special military operation (SMO) has actualized ethical and ideological aspects of war, which led to the corresponding social consequences. One of them is related to the educational-ideological component and manifests itself in the fact that children
M. A. Podlesnaia
doaj   +1 more source

“Napalm Girl” at 50: On Photojournalism and the Ethics of Care

International Journal of Communication, 2023
From the moment of its publication in 1972, the prize-winning photograph “Napalm Girl/Terror of War” was recognized as newsworthy because it exemplified contemporary news values.
Meenakshi Gigi Durham
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The Ethics of War and Peace in Russian Philosophy and the Ethical Consequences of Modern Legal Precedents on Warfare and Armed Forces

Conatus - Journal of Philosophy
The first part of the study is devoted to a comparative analysis of the concepts of the Ethics of War and Peace in Russian philosophy and its influence on the world practice of nonviolence. The second part of the study is devoted to analyzing the impact
Tatiana Minchenko
doaj   +1 more source

WAR, THE PROFESSION OF ARMS AND CHRISTIAN ETHICS [PDF]

Annals: Series on Military Sciences, 2009
In this paper are presented the following issues: some aspects of the teaching of Jesus; the Early Church; Constantine, Ambrose, Augustine and the formulation of the "Just War" Theory; military ethics today; symptoms of moral deterioration in situations ...
Victor DUBBIN
doaj