Results 91 to 100 of about 14,007,730 (234)
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
An Ancient Dilemma: A case study for use in teaching in Engineering Ethics [PDF]
This is an Engineering Ethics case study from the IDEA CETL. The scenario examines the case of a conflict between completing a project on time and within budget and respecting the demands of heritage.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds
core
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
The document was drafted by the Cataloging Ethics Steering Committee (CESC) in consultation with six Working Groups and members of the international cataloging community of practice.
Cataloging Ethics Steering Committee
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This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Ethics Eye is looking for Spotters!
This entry includes a write-up and 2 infographics in English.On January 8, 2024, the Ethics Eye team published a three-slide post on their facebook page encouraging followers and others to join the team as external media ethics violation ...
Ethics Eye
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Ethical issues in clinical research
Thatte Urmila
doaj +1 more source
Should infectious disease modelling research be subject to ethics review? [PDF]
Green B.
europepmc +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Research ethics review in humanitarian contexts: the experience of the independent ethics review board of Médecins Sans Frontières. [PDF]
Ross Upshur +27 more
core +1 more source

