Results 31 to 40 of about 2,047,734 (258)

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Looking through the Narratives of School- based Feeding Program Coordinators: A Phenomenology

International Journal of Multidisciplinary Educational Research and Innovation
This study aimed to explore the narratives of school-based feeding program coordinators, focusing on their experiences, coping mechanisms, and insights in organizing and facilitating feeding programs. A qualitative phenomenological approach was utilized,
Glecyl Jane A. Verallo, Jobell B. Jajalla   +1 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Ethical reflections on phase I clinical trials of anticancer drugs: from a Chinese IRB’s empirical perspective

Holistic Integrative Oncology
Purpose With the rapid development of Phase I clinical trials for anticancer drugs in China, addressing ethical concerns is imperative. In order to safeguard the rights, interests, and well-being of research participants, this paper aims to illustrate ...
Xiaoling Liu, Zhengbo Song, Shuting Tang, Zhaochen Wang, Ji Zhu   +4 more
doaj   +1 more source

The Stories of LGBT Student- leaders: A Multiple Case Study

International Journal of Multidisciplinary Educational Research and Innovation
The purpose of this qualitative study was to unlock the different points of view from LGBT students in their involvement in the field of leadership.
Jhon Lloyd L. Tagmomo, Jobell B. Jajalla
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

The Raison d'Être of Mutual Recognition: An Analysis of the 2015 Reform to Research Ethics Review Policies, Processes and Problems in Québec

Health Reform Observer - Observatoire des Réformes de Santé, 2017
Ethics review is a pre-requisite to conducting research involving humans in Canada, and indeed in most international jurisdictions. The Tri-Council Policy Statement on Ethical Conduct for Research Involving Humans (TCPS2) serves as the national policy ...
Vasiliki Rahimzadeh
doaj   +3 more sources

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

The Development and Implementation of a Quality Improvement Review Committee (QIRC): An Ethical and Pragmatic Imperative

Canadian Journal of Bioethics
Background: In complex academic healthcare systems, quality improvement (QI) projects designed to improve care and enhance learning proliferate, yet there is considerable variation with respect to how, or even whether, these projects receive ethical ...
Sarah E. McMillan, Sarah Tosoni, Kerry-Ann Smith, Betty Chau, Paul Oh, Catriona Steele, Lucas B. Chartier, Ann Heesters   +7 more
doaj   +1 more source

Cubical ethnography: Another kind of fieldwork

Medicine Anthropology Theory, 2020
Studying the contemporary clinic necessitates rethinking what it means to both enter and access ‘the field’. In these Field Notes, I reflect on the beginnings of fieldwork and the processes of crafting research protocols which can stand up to formal ...
Paula Martin
doaj   +1 more source