Results 41 to 50 of about 2,047,734 (258)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Ethical Evaluation and Action Research: Toward New North-South Research Collaborations?
Canadian Journal of Bioethics, 2018 This case study examines the author's experience gaining ethics approval for an action research project, to build capacity for new North-South research collaborations among graduate students trained in health and environment.
Mathieu Feagan
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
Research ethics: ethical review and beyond
Science is a collective endeavor highly dependent on public acceptance and trust. Research findings must be reliable to serve the surrounding society as well as the research community itself. Evidence-based practice and policy recommendations may become ineffective or even dangerous if based on fraudulent research findings.
Elin Palm, Lars Lindblom
openaire +2 more sources
The ethics of peer review in bioethics [PDF]
Journal of Medical Ethics, 2013 A good deal has been written on the ethics of peer review, especially in the scientific and medical literatures. In contrast, we are unaware of any articles on the ethics of peer review in bioethics. Recognising this gap, we evaluate the extant proposals regarding ethical standards for peer review in general and consider how they apply to bioethics. We
David, Wendler, Franklin, Miller
openaire +2 more sources
Frontiers in PharmacologyClinical trials are essential for validating the safety and efficacy of traditional medicines; however, their conduct in Africa is significantly hindered by resource constraints, a lack of standardized regulatory frameworks, and insufficient guidance for
Aisha Gambo +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
A Review of Issues in the U.S. Technology Ethics Review System
Yixue yu zhexueAs ethical review practices have evolved, scholarship on the U.S. system of research ethics review has gradually shifted from procedural discussions toward broader reflections on ethical theories and value orientations.
Yuanbao HOU, Fei WANG
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz +6 more
wiley +1 more source