Results 141 to 150 of about 153,070 (262)

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari, Asif Raza, Hannah Johnson, Nuria Martínez‐Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano   +7 more
wiley   +1 more source

Modulating mycobacterial envelope integrity for antibiotic synergy with benzothiazoles

Life Science Alliance
This study explores benzothiazoles targeting a novel mycobacterial vulnerability, resulting in increased mycobacterial cell envelope permeability and enhanced antibiotic activity.
Eva Habjan, Alexander Lepioshkin, Vicky Charitou, Anna Egorova, Elena Kazakova, Vien QT Ho, Wilbert Bitter, Vadim Makarov, Alexander Speer   +8 more
doaj   +1 more source

Ethidium bromide binding to core particle: comparison with native chromatin

, 1979
Ethidium bromide intercalation into DNA of nuclease digested erythrocyte chromatin and core particle, was followed at low ionic strength by fluorescence measurements, equilibrium dialysis using 14C labelled dye, circular dichroism and electron microscopy.
Champagne, M, Erard, M, Das, G C, Mazen, A, Pouyet, J, Daune, M, Murcia, G,   +6 more
core   +1 more source

Occurrence of Antimicrobial Resistance in Kocuria rhizophila Bacteria Isolated From Salmo munzuricus (Teleostei: Salmonidae) Samples in Natural Resources

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study examined the antibiotic susceptibility of Kocuria rhizophila isolated from Salmo munzuricus samples taken from the Munzur River. The isolates are resistant to Penicillin G, moderately susceptible to gentamicin and tetracycline, and highly susceptible to amoxicillin and ampicillin.
Bülent KAR
wiley   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

Molecular Oral Microbiology, Volume 41, Issue 4, Page 227-238, August 2026.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai, Kaya Yoshida, Yuka Hiroshima, Ayu Ikuta, Mariko Seyama, Yuta Uemura, Hiromichi Yumoto, Kazumi Ozaki   +7 more
wiley   +1 more source

ASSOCIATED ANISOTROPY DECAY OF ETHIDIUM BROMIDE INTERACTING WITH DNA

, 2014
Ethidium Bromide (EB) is a commonly used dye in a deoxyribonucleic acid (DNA) study. Upon an intercalation, this dye significantly increases its brightness and lifetime.
Raut, Sangram, Gryczynski, Ignacy, Sabnis, Sarika, Gryczynski, Zygmunt, Chib, Rahul, Singhal, Preeti   +5 more
core  

Patient‐derived forebrain cortical organoids reveal biphasic tau–MAP6–microtubule axis dysfunction in tauopathy

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION In frontotemporal dementia (FTD), tau detaches from axonal microtubules and forms pathological aggregates. Rather than stabilizing microtubules, tau promotes labile microtubule domains, redefining its role in neurodegeneration and underscoring the need for human models that capture temporal disease progression.
Xiaohuan Sun, Skandha Ramakrishnan, Victor C. Ogbolu, Nicholas M. Kanaan, Celeste M. Karch, Peter W. Baas, Liang Qiang   +6 more
wiley   +1 more source

Introduction of an Antibiotic and Antitumural Drug Replace for Ethidium Bromide in DNA Staining in Agarose Gel Electrophoreses [PDF]

Background & Objectives: Ethidium bromide , a chemical substance with flourscence property and incorporate to DNA , is used in DNA identification in agarose gel electrophoresis.Since this material is very oncogen and has a great usage in molecular ...
اکبری دیباور, محمد
core  

Evaluation of ethidium bromide effects in the life cycle and reproductive behavior of Drosophila melanogaster

, 2020
Research Notes 17 Finally, the present experimental data show the effect of colored light due to the difference in light wavelength on the development of a phenotypic trait from a genotype.
W M Hiesey ; Dobzhansky, J Champion ; Clausen, A P Gupta, R C Lewontin ; Flatt, Th, T, T D Gupta, A P Berry-Wingfield, D D Keck, B Spassky   +9 more
core  

Adipose‐Derived Stem Cells Differentiate Into Insulin‐Producing Cells in 2D Culture With Photobiomodulation: A Comparative Analysis of Wavelength and Fluence Parameters

Cell Biology International, Volume 50, Issue 7, July 2026.
ABSTRACT Diabetes mellitus is a chronic metabolic disorder characterized by the loss or dysfunction of insulin‐producing beta (β) cells. Adipose‐derived stem cells (ADSCs) represent a promising source for generating functional insulin‐producing β cells due to their accessibility and differentiation potential.
O. Daramola, H. Abrahamse, A. Crous
wiley   +1 more source