Results 141 to 150 of about 240,113 (263)

The “Tianyu” Formulation Alleviates Rheumatoid Arthritis by Modulating the NLRP3/Caspase‐1/GSDMD‐Mediated Pyroptosis Pathway

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Proposed signaling pathway by which TY modulates NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis. ABSTRACT This research focuses on exploring the modulation of pyroptosis and its underlying mechanisms via the “Tianyu” formulation (TY), a traditional Chinese medicine, in human rheumatoid arthritis fibroblast‐like synovial cells (RA‐HFLS) and a collagen ...
Yueya Zhu, Xinying Cai, Qiuhan Zheng, Chunqiu Fang, Zhi Pan, Yinghang Wang   +5 more
wiley   +1 more source

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
Ruthenium(II) (Ru(II)) pyrazolyl–pyridine half‐sandwich complexes (C1–C6) were synthesized and structurally characterized as prospective metalloantibiotics. Screening through the Community for Open Antimicrobial Drug Discovery (CO‐ADD) revealed selective activity against Acinetobacter baumannii, with favorable cytotoxicity profiles. Biophysical studies
M. Cassiem Joseph, Sheldon Sookai, Monika Nowakowska, Rotondwa Mphephu, Angela M. Kavanagh, Johannes Zuegg, Mark A. T. Blaskovich, Andrew J. Swarts   +7 more
wiley   +1 more source

Integrating image‐based phenotyping and marker‐assisted selection to optimize the selection of potato clones for chipping and resistance to viruses X and Y

Crop Science, Volume 66, Issue 3, May/June 2026.
Abstract Potato (Solanum tuberosum L.) is the most important non‐cereal crop for global food security. To meet the demands of the processing, potato clones with good frying quality and industrial yield and resistance to major viral diseases are required. This study aimed to integrate image‐based phenotyping and marker‐assisted selection to optimize the
Leticia Novais Padua, Mayra Alejandra Rincón Rueda, Roberto Henrique de Lima Ribeiro, Ivan David Briceño‐Pinzón, Mikael de Paula Brandão, Luciana Aparecida Miguel, José Luis Quiñonez Martínez, Vinicius Samuel Martins, Luciano Donizete Gonçalves, Márcio Fernando Ribeiro de Resende Jr, Mario Henrique Murad Leite Andrade, Lincoln Zotarelli, Vinicius Quintao Carneiro, Lucimara Cruz de Souza, Tiago de Souza Marçal   +14 more
wiley   +1 more source

Environmental and Spatial Processes Drive the Phylogenetic Diversity and Structure of Planktonic Microeukaryotes Revealed by 18S rDNA Metabarcoding in a Tropical Floodplain

Environmental DNA, Volume 8, Issue 3, May–June 2026.
The community structure of photosynthetic planktonic microeukaryotes in the floodplain lakes of the Tocantins‐Araguaia River basin is influenced by a combination of environmental filters and spatial processes. Phylogenetic information from this community highlights the importance of conserving less degraded areas to preserve the evolutionary diversity ...
Jocilaine Santos de Jesus, João Carlos Nabout, Priscilla de Carvalho, Ludgero Cardoso Galli Vieira, Cíntia Pelegrineti Targueta, Diego Ortiz da Silva, Mariana Pires de Campos Telles, José Alexandre Felizola Diniz‐Filho, Thannya Nascimento Soares   +8 more
wiley   +1 more source

The Impact of Genotoxicity in Coke Oven Workers: Systematic Review With Meta‐Analysis

Journal of Applied Toxicology, Volume 46, Issue 5, Page 1460-1475, May 2026.
ABSTRACT This systematic review (SR) with meta‐analysis investigates the genotoxicity potential of coke oven workers (COWs) exposed to polycyclic aromatic hydrocarbons (PAHs) through a comprehensive analysis of studies retrieved from PubMed, SCOPUS, and Web of Science.
Thiago Guedes Pinto, Vinícius Fialho do Nascimento, Giovanna Abreu Holanda Guerra, Wilton Mitsunari Takeshita, Raquel Alves Sales, Andrea Cristina de Moraes Malinverni, Luciana Lopes Guimaraes, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Testing DAT1 and DRD4 Genes in Attention Deficit Hyperactivity Disorder Using a Wide Spectrum of Neurocognitive Batteries

International Journal of Developmental Neuroscience, Volume 86, Issue 3, May 2026.
This study examined DAT1 and DRD4 VNTR polymorphisms and neurocognitive performance in 336 children and adolescents with ADHD and controls using the CNS Vital Signs battery. DAT1 10R/10R showed no significant effects after adjustment, whereas DRD4 4R/4R was associated with reduced cognitive flexibility. ABSTRACT Attention‐deficit/hyperactivity disorder
Gül Ünsel‐Bolat, Hilmi Bolat, Sema Yıldırım, Semiha Özgül, Akın Tahıllıoğlu, Kemal Utku Yazıcı, Ali Bacanlı, Erhan Parıltay, Duygu Aygüneş‐Jafari, Buket Kosova, Luis Augusto Rohde, Haluk Akın, Eyüp S. Ercan   +12 more
wiley   +1 more source

A Multicellular 3D GelMA‐Based Colorectal Cancer Model for Chemotherapeutic Responses

Macromolecular Bioscience, Volume 26, Issue 5, May 2026.
The development of a GelMA‐based, multicellular 3D in vitro platform designed to more faithfully recapitulate the colorectal cancer (CRC) tumor microenvironment for drug screening applications. The platform integrates a vascularized hydrogel matrix, cancer‐associated fibroblasts, and M2‐polarized macrophages. The translational relevance of the platform
Seyfure Adıgüzel, Sevde Altuntaş, Şevval Çelikten, Mehmet Cem Gündüz, Merve Güdül Bacanlı   +4 more
wiley   +1 more source

Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS

PROTEOMICS, Volume 26, Issue 5, Page 27-36, May 2026.
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor, Austin Lipinski, Paul R. Langlais, Jacob C. Schwartz   +3 more
wiley   +1 more source

Protective Effect of Intracellular Compounds of Lactobacillus plantarum on Goat Sperm Quality During Cryopreservation

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Intracellular compounds from Lactobacillus plantarum were added to a goat sperm cryopreservation extender. A concentration of 20 µL/mL improved post‐thaw sperm quality, whereas higher concentrations (80–100 µL/mL) had detrimental effects. ABSTRACT Background Cryopreservation of sperm is a key strategy for preserving and transmitting the genetic traits ...
Farshad Ariyan, Amjad Farzinpour, Abbas Farshad, Aram Sharifi   +3 more
wiley   +1 more source

Bovine Tuberculosis in Raw Milk: A Herd‐Level Prevalence Study by PCR and ELISA Testing in Sylhet Region of Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study reveals the prevalence of bovine TB from vendor's milk and herd‐level testing using molecular approach: PCR and ELISA test highlighting the risk factor dynamics that shape bovine tuberculosis (bTB) occurrence in Sylhet region of Bangladesh. The findings advance understanding of bTB for diagnostics and surveillance strategies.
Lipi Rani Basak, Md‐Tariqul Islam, Sabuj kanti Mazumder, Dewan Mohammad Mahbubur Rajib, Mohammad Nizam Uddin Chowdhury, Md. Irtija Ahsan, Md. Mukter Hossain, Sultan Ahmed, A. T. M. Mahbub‐e‐Elahi   +8 more
wiley   +1 more source