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Neurotoxic Effects of Ethidium Bromide, Rat
1988Pathologic lesions are produced by a direct exposure of the central and peripheral nervous tissues to ethidium bromide which is a red dye. Therefore the lesion appears red or reddish-orange and softer than the surrounding tissue.
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Complex formation between ethidium bromide and nucleic acids
Journal of Molecular Biology, 1965The interaction between ethidium bromide and nucleic acids shows a pronounced metachromatic effect which has been used to obtain quantitative data on the process of complex formation. Ethidium binds strongly to both DNA and RNA at sites which appear to be saturated when one drug molecule is bound for every 4 or 5 nucleotides.
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Ethidium bromide resistance and enhancement of mitochondrial recombination
Molecular and General Genetics MGG, 1974In some yeast cytoplasmic mutants, ethidium bromide resistance is expressed at the mitochondrial level. In homosexual crosses it leads to an enhanced recombination between two linked mitochondrial genes controlling chloramphenicol and erythromycin resistance or sensitivity, but recombination is still reciprocal.
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