Results 221 to 230 of about 246,567 (336)

Inhibition of mTOR Prevents ROS Production Initiated by Ethidium Bromide-Induced Mitochondrial DNA Depletion. [PDF]

Front Endocrinol (Lausanne), 2014
Nacarelli T, Azar A, Sell C.
europepmc   +1 more source

Integrated In Silico and In Vitro Study of Copper Nanocatalyzed Carbonyl‐Functionalized Triazoles—Inducing S Phase Cell Cycle Arrest and Apoptosis in MCF‐7

ChemistryOpen, Volume 15, Issue 1, January 2026.
A targeted drug discovery pipeline identified novel copper‐nanocatalyzed carbonyl‐functionalized triazoles as potent breast cancer therapeutics (selectivity index up to 4.44). Lead compounds (3i, 3j) induced apoptosis in breast cancer cells (MCF‐7) by modulating BAX/BCL2, causing reactive oxygen species (ROS)‐mediated glutathione (GSH) depletion ...
Joydip Mondal, Tiasha Dasgupta, Chitluri Kiran Kumar, Prasanth Babu Nandagopal, Sadananda Mal, Sourav Paul, Aishwarya S, Chayan Pandya, Isaac Arnold Emerson, Venkatraman Manickam, Akella Sivaramakrishna   +10 more
wiley   +1 more source

Fibroblast‐specific palladin drives kidney fibrosis via MRTF–SRF signaling

The Journal of Pathology, Volume 268, Issue 1, Page 40-53, January 2026.
Abstract Fibrosis is a common end‐stage pathway of progressive chronic kidney diseases. Previously we demonstrated that myocardin‐related transcription factor (MRTF)–serum response factor (SRF) signaling drives the expression of fibrosis‐related molecules through actin cytoskeleton dynamics in renal fibroblasts.
Naoki Yamamoto, Norihiko Sakai, Yuta Yamamura, Daichi Kaikoi, Daiki Hayashi, Takahiro Matsuno, Akihiko Koshino, Keisuke Sako, Keisuke Horikoshi, Takahiro Yuasa, Akira Tamai, Taichiro Minami, Megumi Oshima, Shiori Nakagawa, Shinji Kitajima, Akinori Hara, Miho Shimizu, Jumpei Terakawa, Shin‐ichi Horike, Takiko Daikoku, Atsushi Mizokami, Hiroko Ikeda, Moeno Kadoguchi, Hiroshi Arakawa, Sumio Ohtsuki, David Lagares, Takashi Wada, Yasunori Iwata   +27 more
wiley   +1 more source

Assessment of the Antimicrobial Activity of <i>Cistus salviifolius</i> L. and <i>Helichrysum stoechas</i> (L.) DC Extracts and Their Synergistic Potential with Conventional Antibiotics Against <i>Staphylococcus aureus</i>. [PDF]

Int J Mol Sci
Coimbra A, Luís Â, Gaspar PD, Ferreira S, Duarte AP.   +4 more
europepmc   +1 more source

The DNA intercalators ethidium bromide and propidium iodide also bind to core histones. [PDF]

FEBS Open Bio, 2014
Banerjee A, Majumder P, Sanyal S, Singh J, Jana K, Das C, Dasgupta D.   +6 more
europepmc   +1 more source

Development and Characterization of Copaiba Oil‐Loaded Polymeric Nanocapsules With Enhanced Antitumor Activity Against Breast Cancer Cells

Particle &Particle Systems Characterization, Volume 43, Issue 1, January 2026.
The present study developed and characterized a novel copaiba oil polymeric nanoparticle (NPOC), which was efficiently internalized by breast cancer cells, exhibited greater cytotoxicity and selectivity than free copaiba oil and standard drug doxorubicin. NPOC also reduced tumor growth and migration in 3D models.
Karinne Kelly Gadelha Marques, Allesya Lara Dantas Formiga, Ramon Ramos Marques de Souza, Isione Oliveira Castro, Heivila Monique da Silva Alexandre, Igor Gabriel da Silva Ramalho, Érika Raisla Melquiades Pereira, Lucas Medeiros Martins Carvalho, Marianna Vieira Sobral, Francisco Humberto Xavier Júnior, Juan Carlos Ramos Gonçalves   +10 more
wiley   +1 more source

The Resistance-Nodulation-Division efflux pump EefABC is highly conserved within lineages of <i>E. coli</i> commonly associated with infection. [PDF]

Microb Genom
Pugh HL, Darby EM, Burgess L, Colclough AL, John AM, Dunn S, Connor C, Perry EA, McNally A, Bavro VN, Blair JMA.   +10 more
europepmc   +1 more source

Ethidium bromide binding to polyriboguanylic acid [PDF]

Biopolymers and Cell, 1989
openaire   +1 more source

Electron paramagnetic resonance studies of spin-labelled ethidium bromide DNA interactions [PDF]

, 1986
D. J. Keeble
openalex  

RNAi‐mediated gene silencing of a 26S proteasome subunit increases mortality of the Japanese beetle Popillia japonica

Pest Management Science, Volume 82, Issue 1, Page 1066-1078, January 2026.
We propose the regulatory particle non‐ATPase subunit 6 of the 26S proteasome as a first good promising RNA interference target candidate to control the Japanese beetle Popillia japonica. This will help to optimize a double‐stranded RNA insecticide against this priority pest with low off‐target effects on pollinators on a gene sequence‐based prediction.
Giulia Lucetti, Simona Abbà, Gabriele Pesavento, Elena Fanelli, Francesca De Luca, Elia Battagini, Stefano Cazzaniga, Matteo Ballottari, Diletta Frizzon, Nicola Mori, Luciana Galetto   +10 more
wiley   +1 more source