Results 211 to 220 of about 240,113 (263)

A synthesis of labeled ethidium bromide

Archives of Biochemistry and Biophysics, 1974
Abstract A method is described for the synthesis of labeled ethidium (3,8-diamino-5-ethyl-6-phenyl phenanthridinium) bromide. Based on benzoic acid, the radioactive precursor used, the yield is 15% of a compound that is indistinguishable from authentic ethidium bromide in its absorption spectra (uv, visible, ir), Chromatographie behavior, and ...
R, De Nobrega Bastos, H R, Mahler
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Yeast mutants resistant to ethidium bromide

Molecular and General Genetics MGG, 1973
Yeast mutants resistant to ethidium bromide have been isolated among sensitive grande cells (ϱ+) for their ability to grow on glycerol in the presence of the dye. Mutant cells are also resistant to acriflavin and do not yield petites (ϱ-) when grown on galactose with the mutagen.
M, Gouhier, J C, Mounolou
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Synthesis of 6-14C-ethidium bromide

Analytical Biochemistry, 1972
Abstract The preparation of 6- 14 C-ethidium bromide of high specific radioactivity is described. The synthesis starts from 14 C-carboxyl-labeled benzoic acid and 4,4′-dinitro-2-aminodiphenyl. The crude compound was purified by chromatography on aluminum oxide.
F J, Loomeijer, A M, Kroon
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Crystal structure of ethidium bromide

Journal of Crystal and Molecular Structure, 1971
Crystals of ethidium bromide (2,7-diamino-9-phenyl-10-ethylphenanthridinium bromide) monohydrate are monoclinic,a = 9·577,b = 10·698,c = 20·242 A, β = 106·34 °,Z = 4, space groupP21/c. The structure was determined with CuKα. diffractometer data by direct methods, and was refined by full-matrix least-squares methods toR = 0·058 for 2151 observed ...
E. Subramanian, James Trotter, Charles E. Bugg   +2 more
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Decontamination of Ethidium Bromide Spills

Applied Industrial Hygiene, 1989
Abstract Samples of stainless steel, Formica, glass, and vinyl floor tile and the filters of transilluminators were contaminated with ethidium bromide and cleaned either by wiping once with a paper towel soaked in an aqueous solution of sodium nitrite and hypophosphorous acid followed by five wipes with wet towels or by wiping six times with only wet ...
George Lunn, Eric B. Sansone
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Mitochondrial membranes and mutagenesis by ethidium bromide

Journal of Supramolecular Structure, 1972
AbstractThe conversion of wild type (ρ+) to cytoplasmic petites (ρ−) in Saccharomyces cerevisiae, à mutation in mitochondrial DNA, can be brought about with high efficiency by low concentrations of ethidium bromide (EB). The rate and extent of mutagenesis and its expression can be influenced, and even reversed, by a number of genetic lesions, agents or
H R, Mahler, P S, Perlman
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Ethidium bromide enhancement of frameshift mutagenesis caused by photoactivatable ethidium analogs

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1979
Ethidium azide analogs (3-amino-8-azido-ethidium monoazide and ethidium diazide) have been developed as photosensitive probes in order to analyze directly the reversible in vivo interactions of ethidium bromide. Our preliminary observations [11], relating the mutagenic potential of the monoazide analog of ethidium, have been extended and refined, using
L W, Yielding, B R, Brown, D E, Graves, K L, Yielding   +3 more
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Metabolism of ethidium bromide in rats.

Drug Metabolism and Disposition, 1981
The biliary excretion products recovered after iv administration of ethidium bromide to rats were found to consist of: unchanged drug, 8-acetylethidium, and an 8-acetylated hydroxylated metabolite. Proofs of structure were obtained by field desorption mass spectroscopy and 1H NMR, which indicated that the latter metabolite is probably substituted at ...
C, Fraire, P, Lecointe, C, Paoletti
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Ethidium Bromide Interaction with Poly(G)

Biophysical Reviews and Letters, 2014
In current work we investigate the interaction between polyguanylic acid and Ethidium Bromide ( EtBr ) and the changes of thermodynamic parameters due to those interactions by spectrophotometric methods. From the binding isotherms, binding constants were calculated for three different temperatures and the changes of Gibbs free energy, entropy and ...
Poghos H. Vardevanyan, Marine A. Parsadanyan, Mikayel V. Minasyants   +2 more
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Resistance to ethidium bromide inAspergillus nidulans

Experientia, 1979
A mutant ofAspergillus nidulans resistant to ethidium bromide was isolated and the semi-dominant gene responsible for this resistance was allocated on linkage group II at 17.42±3.05 units of recombination from thewA3 gene. The gene also confers cross-resistance to acriflavin, malachite green and crystal violet.
M. E. Scarazzatti, R. Bonatelli, J. L. Azevedo   +2 more
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