Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]
, 2016 Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A. +3 more
core +2 more sources
The effect of intrahippocampal injection of estradiol on spatial memory in male rats during multiple sclerosis disease [PDF]
Journal of Advanced Biomedical Sciences, 2014 Background & Objective: Multiple sclerosis (MS) is a demyelinating disease of central nervous system, which is approximately two to three times more common in women than men. It was suggested that sexual hormones affect MS disease.
Vahideh Zarrin +2 more
doaj +2 more sources
Synthesis and Neuropharmacological Evaluation of Some Novel Quinoxaline 2, 3-Dione Derivatives
The Scientific World Journal, 2012 Quinoxaline-2, 3-dione obtained from cyclocondensation reaction of o-phenylene diamine with oxalic acid was reacted with three different ketones and formaldehyde to give the corresponding Mannich bases in satisfactory yield.
Selvaraj Jubie +2 more
doaj +1 more source
Hypoxia-induced mitochondrial stress granules
Cell Death and Disease, 2023 Perturbations of mitochondrial proteostasis have been associated with aging, neurodegenerative diseases, and recently with hypoxic injury. While examining hypoxia-induced mitochondrial protein aggregation in C.
Chun-Ling Sun +2 more
doaj +1 more source
DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores [PDF]
, 1990 Dynemicin is a hybrid containing anthraquinone and enediyne cores, which contribute to binding and cleavage of DNA, respectively. DNA strand scission by the antitumor antibiotic is significantly enhanced by the addition of NADPH or thiol compounds.
Konishi, Masataka +3 more
core +1 more source
Energetics and Mechanism of Drug Transport Mediated by the Lactococcal Multidrug Transporter LmrP [PDF]
, 1996 The gene encoding the secondary multidrug transporter LmrP of Lactococcus lactis was heterologously expressed in Escherichia coli. The energetics and mechanism of drug extrusion mediated by LmrP were studied in membrane vesicles of E. coli. LmrP-mediated
Bolhuis, Henk, +6 more
core +1 more source
Genetics & Applications, 2023 Agarose gel electrophoresis is a routinely employed experimental technique for visualizing nucleic acids, typically combined with ethidium bromide or some other molecular dye staining and a UV transilluminator.
Ryosuke Ishii
doaj +1 more source
HLA-G: expression in human keratinocytes in vitro and in human skin in vivo [PDF]
, 1994 Classical, polymorphic major histocompatibility complex class I molecules are expressed on most nucleated cells.They present peptides at the cell surface and, thus, enable the immune system to scan peptides for their antigenicity.
Ulbrecht, M. +7 more
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Transition on the entropic elasticity of DNA induced by intercalating molecules
, 2007 We use optical tweezers to perform stretching experiments on DNA molecules when interacting with the drugs daunomycin and ethidium bromide, which intercalate the DNA molecule.
Ferreira, M. C. +2 more
core +1 more source
Ethidium bromide binding to DNA cryogels
Reactive and Functional Polymers, 2013 Abstract The interaction of the classical intercalator ethidium bromide (EtBr) with the double helical network strands of DNA cryogels was investigated. The cryogels were prepared starting from aqueous solutions of DNA (about 2000 base pairs long) at −18 °C using 1,4-butanediol diglycidyl ether crosslinker under various reaction conditions.
Karacan, Pinar, Okay, Oguz
openaire +3 more sources