Results 61 to 70 of about 153,070 (262)

Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Parabens (PBs) are compounds widely used as preservatives in personal care products, food, and pharmaceuticals. Methylparaben (MePB) is the most used by different industries due to its chemical properties and low cost. The high daily human exposure to these compounds has raised concerns about their potential effects on health, particularly on ...
Yenny Ramírez‐Jara   +11 more
wiley   +1 more source

Zaleya decandra exerts anti-cancer activity in HCT-116 cancer cells by impairing mitochondrial activity

open access: yesBangladesh Journal of Pharmacology, 2019
An attempt has been made to investigate the role of Zaleya decandra on the survival of HCT colon cancer cells in vitro. The cell viability and apoptosis were assessed using MTT assay and acridine orange/ethidium bromide staining, respectively ...
Malarvizhi Deivasigamani   +4 more
doaj   +1 more source

Reversible and irreversible pollutant-induced bacterial cellular stress effects measured by ethidium bromide uptake and efflux.

open access: yes, 2012
Chemical pollution is known to affect microbial community composition but it is poorly understood how toxic compounds influence physiology of single cells that may lay at the basis of loss of reproductive fitness.
Czechowska, K., van der Meer, J.R.
core   +1 more source

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara   +4 more
wiley   +1 more source

Reversible and Irreversible Pollutant-Induced Bacterial Cellular Stress Effects Measured by Ethidium Bromide Uptake and Efflux

open access: yes, 2016
Chemical pollution is known to affect microbial community composition but it is poorly understood how toxic compounds influence physiology of single cells that may lay at the basis of loss of reproductive fitness.
Jan Roelof van der Meer (152275)   +1 more
core   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos   +4 more
wiley   +1 more source

The electrochemical characterization of ethidium bromide

open access: yes, 1991
Electrochemical Characterization of ethidium bromide (2,7-diamino-9-phenyl-10-ethylphenathridinium bromide) is described The voltammetric and polarographic behavior of ethidium bromide was compared with that of a similar compound, triphosphopyridine ...
Stanley, Gina Ann
core   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

Comparison of techniques for DNA extraction and agarose gel staining of DNA fragments using samples of Cryptosporidium

open access: yesVeterinární Medicína, 2013
Differentiating between the Cryptosporidium species and their subtypes using only microscopy is impossible. Therefore, molecular tools are indispensable for accurate species and subtype diagnosis.
M.C.M. Couto   +3 more
doaj   +1 more source

Targeting fibrosis in the treatment of lower urinary tract dysfunction

open access: yesThe Journal of Pathology, EarlyView.
Abstract Benign prostatic hyperplasia (BPH) is a widely prevalent age‐associated disease that is the main contributor to lower urinary tract dysfunction (LUTD) in aging men. Although prostate fibrosis has been recognized as a contributor to BPH pathophysiology, there are not any clinically available therapeutics that target this aspect of disease ...
Ajinkya R Limkar   +6 more
wiley   +1 more source

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