Graphic Mining of High-Order Drug Interactions and Their Directional Effects on Myopathy Using Electronic Medical Records [PDF]
We propose to study a novel pharmacovigilance problem for mining directional effects of high-order drug interactions on an adverse drug event (ADE). Our goal is to estimate each individual risk of adding a new drug to an existing drug combination.
Chakraborty, A. +8 more
core +1 more source
Hormonal treatments for endometriosis (combined oral contraceptives/progestin‐only pills) do not show increased psychological or sexual risks compared with placebo. When pain is effectively controlled, these therapies appear well tolerated and may improve overall well‐being.
Noemi Salmeri +5 more
wiley +1 more source
Cardiovascular Health in Women—Across the Lifespan
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar +5 more
wiley +1 more source
Comparison of Endometrial Thickness with Concomitant Administration of Sildenafil Citrate and Ethinyl Estradiol vs Ethinyl Estradiol Alone for Frozen Embryo Transfer [PDF]
Introduction: Infertility is one of the common medical issues in today’s world. One of the common causes of infertility is the lack of implantation of the embryo.
Mahnaz Yavangi +3 more
doaj +1 more source
Suggestive hypothesis on a case report: Patient presenting with cyclical ovarian cysts coupled to increased cholestatic enzymes [PDF]
We describe the case of a childbearing-age woman presenting with spontaneous recurrent functional ovarian cysts and, more interestingly, chronic and asymptomatic elevation of cholestatic parameters.
Cafaro, G. +5 more
core +1 more source
Pills-related severe adverse events: A case report in Taiwan
Objective: To review and evaluate the potential adverse effects of these oral contraceptives (OCP) to overweight women. Case Report: A 19-year-old college student, with a body mass index (BMI) of 35.2 kg/m2, who received 2 months of OCP containing ...
Ching-Hui Chen +4 more
doaj +1 more source
Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. [PDF]
BACKGROUND: Prior studies have shown that switching patients from inducing antiepileptic drugs (AEDs) to lamotrigine, levetiracetam, or topiramate reduces serum lipids and C-reactive protein (CRP). These studies were all of short duration, and some drugs,
Chervoneva, Inna +6 more
core +2 more sources
Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley +1 more source
Ovarian hormones modulate multidrug resistance transporters in the ovary
Background Multidrug resistance transporters (MDRs) are transmembrane proteins that efflux metabolites and xenobiotics. They are highly conserved in sequence and function in bacteria and eukaryotes and play important roles in cellular homeostasis, as ...
Lynae M Brayboy +4 more
doaj +1 more source
Oral contraceptive progestins and angiotensin-dependent control of the renal circulation in humans [PDF]
Oral contraceptive (OC) use is associated with increased intra-renal renin-angiotensin-aldosterone system (RAA System) activity and risk of nephropathy, though the contribution of progestins contained in the OC in the regulation of angiotensin-dependent ...
Ahmed, Sofia B. +3 more
core +1 more source

