Efficacy and safety of desogestrel/ethinylestradiol 150/20 flexible extended regimen (FREEDOM 150/20) in dysmenorrhea: phase 3 study in Japan [PDF]
F&S ReportsObjective: To evaluate the efficacy and long-term safety of a user-driven flexible extended regimen of desogestrel 150 μg/ethinylestradiol 20 μg (DSG/EE 150/20) for the treatment of primary or secondary dysmenorrhea in women from Japan.
Kaori Koga, M.D., Ph.D. +5 more
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Ethinylestradiol Transfer into Breast Milk of Women Using Low-Dose Combined Hormonal Contraception Is Negligible [PDF]
Open Access Journal of ContraceptionLior Segev,1,2,* Avigail Ben Zimra,1,* Gideon A Weitzman,2 Naamah Bloch,1 Itay Pitussi,3 Tatiana Alkhazov,4 Natalya M Kogan,4 David Peleg,1,5 Abraham O Samson,1 Inbar Ben Shachar1,5 1Azrieli Faculty of Medicine, Bar Ilan University, Safed,
Segev L +9 more
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Metabolic consequences of perinatal bisphenol A and 17α-Ethinylestradiol exposure manifest in circadian alterations of energy homeostasis in adult male mice [PDF]
Frontiers in EndocrinologyIntroductionEnvironmental estrogenic chemicals can cross the maternal–fetal barrier and disrupt endocrine and metabolic regulation in the developing embryo/fetus.
Imre Kalló +8 more
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A Systematic Review of Estrogens as Emerging Contaminants in Water: A Global Overview Study from the One Health Perspective [PDF]
Journal of XenobioticsThe widespread presence of estrogens in aquatic environments represents a One Health concern, as it simultaneously threatens environmental integrity, wildlife health, and human well-being.
Rhitor Lorca da Silva +8 more
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Efficacy and safety of drospirenone-containing microdosage combined oral contraceptive use with starting contraception [PDF]
Гинекология, 2018 Androgen-dependent dermopathy, as well as premenstrual syndrome of varying severity in young women, can cause emotional depression, difficulties in social adaptation and even depressive disorders. The aim of the study was to study the safety and efficacy
A R Khachaturian +2 more
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Role of Estrogens in Menstrual Migraine
Cells, 2022 Migraine is a major neurological disorder affecting one in nine adults worldwide with a significant impact on health care and socioeconomic systems. Migraine is more prevalent in women than in men, with 17% of all women meeting the diagnostic criteria ...
Rossella E. Nappi +5 more
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Systemic hormonal contraception and risk of venous thromboembolism
Acta Obstetricia et Gynecologica Scandinavica, 2022 Introduction The increased risk of venous thromboembolism associated with the use of hormonal contraception is well recognized, but evidence regarding hormonal contraception containing natural estradiol is limited.
Oskari Heikinheimo +5 more
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Reproductive Medicine and Biology, 2021 Purpose We aimed to evaluate the efficacy and safety of 28‐day Cyclic and 84‐day Extended regimens of NPC‐16 (ethinylestradiol 0.02 mg plus levonorgestrel 0.09 mg) in patients with dysmenorrhea.
Tasuku Harada, Mikio Momoeda
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The use of Dimia for the treatment of premenstrual syndrome in adolescent girls [PDF]
Гинекология, 2019 Today, premenstrual syndrome (PMS) remains one of the relevant issues of adolescent gynecology. The difficulty in treatment of PMS in adolescent girls is associated with a large number of factors. The combination of hormonal, neuro-vegetative, metabolic,
Elena V Sibirskaya, Gulnoza M Turgunova
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Pharmaceuticals, 2022 The disease caused by SARS-CoV-2 is still considered a global pandemic. Transdermal patches (TP) with immunoregulators such as estrogen and progesterone compounds could be a feasible option to treat COVID-19 because of their accessibility and relative ...
Cortés-Algara Alfredo +11 more
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