Results 161 to 170 of about 1,636,579 (314)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Measuring Segregation [PDF]

We propose a set of axioms for the measurement of school-based segregation with any number of ethnic groups. These axioms are motivated by two criteria. The first is evenness: how much do ethnic groups’ distributions across schools differ?
Frankel, David M., Volij, Oscar
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Pain amongst ethnic minority groups of South Asian origin in the United Kingdom: a review [PDF]

, 1999
Panganani Njobvu, Isabelle M. Hunt, Daniel Pope, Gary J. Macfarlane   +3 more
openalex   +1 more source

Unemployment, economic status and ethnic politics: A case study of Karachi [PDF]

Regional-based quota in public sector employment was always considered as one of the important cause of the ethnic politics in Pakistan and particularly in Karachi.
Mehar, Ayub
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Review of Barriers to Engaging Black and Minority Ethnic Groups in Physical Activity in the United Kingdom

, 2009
Sejlo A. Koshoedo, Padam Simkhada, Edwin van Teijlingen   +2 more
openalex   +2 more sources

Do enclaves matter in immigrants’ self-employment decision? [PDF]

This paper uses 2000 U.S. Census data to study the determinants of self-employment decisions among immigrants. It outlines a theoretical framework for analyzing the role of ethnic enclaves in the self-employment decision of immigrants that captures ...
Maude Toussaint-Comeau
core  

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Experiences of healthcare services among racial and ethnic groups in the U.S. [PDF]

Prev Med Rep
Bonsignore S, Samples H, Stone EM.
europepmc   +1 more source