Results 91 to 100 of about 481,141 (354)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Bend It Like Beckham: Ethnic Identity and Integration [PDF]

We propose a theoretical framework to study the determinants of ethnic and religious identity along two distinct motivational processes which have been proposed in the social sciences: cultural conformity and cultural distinction.
Bisin, Alberto, Patacchini, Eleonora, Verdier, Thierry, Zenou, Yves   +3 more
core   +3 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Does Fiscal Decentralization Dampen All Ethnic Conflicts? The heterogeneous Impact of Fiscal Decentralization on Local Minorities and Local Majorities [PDF]

Fiscal decentralization is widely proposed as an efficient means to accommodate ethnic violence. Yet while most of the econometric cross-country studies supports this view, case studies offer mixed results. In this paper, it is argued that this is partly
Tranchant, Jean-Pierre
core   +1 more source

Credit access in the Northern Mountainous Region of Vietnam: do ethnic minorities matter? [PDF]

, 2015
By using the Bayesian Approach to address the problem of model uncertainty and a binary logit regression, this paper examines the credit accessibility of ethnic minority households compared to Kinh households in one of the poorest regions of Vietnam–the ...
Anh, Nguyen Thi Lan, Luan, Do Xuan
core   +1 more source

Significantly Increased Public Interest in Sleep Disorder during the COVID-19 Pandemic: An Analysis of Google Trends Data

Journal of Education, Health and Sport
Background: The COVID-19 pandemic has had a profound impact on sleep disorders. Previous studies have shown that people's sleep time is delayed. Methods: Analyze the public's interest to the keyword "sleep disorder" during the COVID-19 pandemic from ...
Qinyi Tan, Xiaolu Chen, Yidan Cui, Hao Sun, Luyan Teng   +4 more
doaj   +1 more source

Analysis on the semantic evolution of Chinese Gan dialect from the perspective of cognition

SHS Web of Conferences, 2016
The meaning of a word is the reflection of social life, and it is the result of the cognition of the object, phenomenon and relationship through the mental activity. The development and changes of lexical mean-ings essentially reflect the development and
Xiao Jiugen, Chen Xijuan, Xiong Lingjun
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Ethnicity and the Jury System [PDF]

, 2001
Discrimination in the jury system has been a matter of constitutional and ethical concern at least since the mid-nineteenth century. Ethnic and linguistic minorities have been disadvantaged by the use of the peremptory challenge, statutory requirements ...
Welch, Ashton Wesley
core   +1 more source