Results 71 to 80 of about 1,177,960 (347)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Using materials by module in teaching Maths-teaching Methodology module for maths students at Lao teacher training colleges

Vietnam Journal of Education, 2020
Among popular teaching approaches, teaching by module is attracting educationers. In education, the module approach is linked to the teaching technology ideology, which is a modern way of structuring or organizing the compilation of teaching content so ...
Trung Tran, Done Sophida
doaj  

Ethnicity and health inequalities: an empirical study based on the 2010 China survey of social change (CSSC) in Western China

BMC Public Health, 2020
Background In China, ethnic minorities often live in frontier areas and have a relatively small population size, and tremendous social transitions have enlarged the gap between eastern and western China, with western China being home to 44 ethnic ...
Y. J. Wang, X. P. Chen, W. J. Chen, Z. L. Zhang, Y. P. Zhou, Z. Jia   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The European Dimension of the Political Representation of Minorities [PDF]

, 2009
The political integration of ethnic minorities is one of the most challenging tasks facing the countries of post-communist Europe. The roads to political representation in the mainstream political process are numerous and diverse. The EU accession of the
Stefanova, Boyka
core  

Oppositional Identities and Employment for Ethnic Minorities: Evidence from England [PDF]

Where a community or group is socially excluded from a dominant group, some individuals of that group may identify with the dominant culture and others may reject that culture.
Battu, Harminder, Zenou, Yves
core   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Complementary stereotyping of ethnic minorities predicts system justification in Poland [PDF]

, 2015
We investigate the phenomenon of complementary stereotyping of ethnic minorities in Poland and its relationship to system justification. Using results from a nationally representative survey we test the hypothesis that complementary stereotypes—according
Jost, John T., Winiewski, M., Cichocka, Aleksandra, Bilewicz, Michał, Bukowski, Marcin, Bukowski, M., Winiewski, Mikołaj, Bilewicz, Michal   +7 more
core   +1 more source

Introduction : Divided against themselves? Ethnic minorities, nationalism, and fractured anti-fascist identities

, 2023
Europe contained 36 million people classified as ethnic minorities in the interwar period. The vast majority, 25 million, lived in East Central Europe. With ultranationalism, xenophobia and racism rampant among the majority populations, this was a hotbed
Braskén, Kasper, Ahlbäck, Anders,
core   +1 more source