Results 51 to 60 of about 1,752,841 (343)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The Logic and Direction of the Digital-Intelligent Development of Higher Vocational College Teachers' Pedagogical Content Knowledge

open access: yesJiaoshi jiaoyu xuebao
Under the background of the deep coupling of digital technology and intelligent technology, and the accelerated reconstruction of vocational education ecology, digital-intelligent development of higher vocational teachers' Pedagogical Content Knowledge ...
ZHU Dequan, LI Xue
doaj   +1 more source

Factors influencing the higher incidence of tuberculosis among migrants and ethnic minorities in the UK

open access: yesF1000Research, 2018
Migrants and ethnic minorities in the UK have higher rates of tuberculosis (TB) compared with the general population. Historically, much of the disparity in incidence between UK-born and migrant populations has been attributed to differential pathogen ...
S. Hayward   +3 more
semanticscholar   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Reviewing the Problems in Rural Teacher Policy Instrumentsand Optimization Strategies: Based on the Analysis Framework of McDonnel and Elmore

open access: yesJiaoshi jiaoyu xuebao
As a comprehensive education and livelihood project, the construction of the rural teacher workforce is an important aspect of promoting the strategy of rural revitalization and deepening educational reform.
CHEN Hui, LI Chencheng
doaj   +1 more source

Has the digital economy improved income inequality for ethnic minorities? The case of China

open access: yesHeliyon, 2023
This paper examines how China's ethnic minorities' income equality has changed due to the digital economy's development. The study focuses on the critical analysis of the legal system by juridical analysis combined with doctrinal and textual analysis ...
Kailiang Ma, He Zhang
doaj   +1 more source

Media policy for ethnic and national minorities in Poland, the Czech Republic and Slovakia [PDF]

open access: yes, 2003
This chapter describes legal, institutional and professional frameworks for media policy concerning national and ethnic minorities in Poland, the Czech Republic and Slovakia.
Klimkiewicz, Beata
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Declining returns of secondary vocational education on subjective class identity across generations and time periods

open access: yesHumanities & Social Sciences Communications
This study explores the association of secondary vocational education (SVE) on subjective class identification in China, focusing on comparisons with compulsory and academic high school education, and analyzing regional and historical variations.
Penghui Wu, Ming Zhang, Demei Yang
doaj   +1 more source

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