Results 61 to 70 of about 454,014 (283)

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

An Expert Stakeholder's View on European Integration Challenges [PDF]

open access: yes
The standard approach of analysing gaps in social and labor market outcomes of different ethnic groups relies on analysis of statistical data about the affected groups.
Amelie Constant   +2 more
core   +3 more sources

Understanding the relationship between education-based hypergamy and women's social interaction in China: mediating roles of career aspirations and social distrust

open access: yesFrontiers in Public Health
BackgroundEducation-based hypergamy (EBH) is a key factor influencing the social interaction (SI) of women in China. Women in education-based hypergamous marriages, where they have lower education levels than their spouses, often face unique challenges ...
Penghui Wu, Ming Zhang, Senhao Xiong
doaj   +1 more source

Does education improve employee benefits in Vietnam? The first evidence from matched employer–employee data

open access: yesCogent Education, 2019
Based on a uniquely matched firm-worker panel dataset for 2013 and 2015, this study is the first to consider the effect of education on employee benefits in terms of wages and quality of employment. We find that only college or university education has a
Tran Trung   +3 more
doaj   +1 more source

Characterizations of Pacific Island people in the New Zealand press [PDF]

open access: yes, 2005
Researchers have documented how ethnic minorities are often disadvantaged in mainstream media coverage, which function to silence minority voices and to privilege majority voices.
Barnett, Alison Reremoana   +5 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Knowledge, attitude and willingness of different ethnicities to participate in cadaver donation programs.

open access: yesPLoS ONE, 2020
Knowledge, attitude and willingness of ethnic minorities in China towards cadaver donation programs were assessed. Questionnaire and interviews were conducted to investigate Yi, Bai, Hani, Dai and Han ethnicities.
Xiang Zhang   +7 more
doaj   +1 more source

Does Fiscal Decentralization Dampen All Ethnic Conflicts? The heterogeneous Impact of Fiscal Decentralization on Local Minorities and Local Majorities [PDF]

open access: yes
Fiscal decentralization is widely proposed as an efficient means to accommodate ethnic violence. Yet while most of the econometric cross-country studies supports this view, case studies offer mixed results. In this paper, it is argued that this is partly
Tranchant, Jean-Pierre
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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