Results 101 to 110 of about 17,961,033 (290)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
PUBLIC ADMINISTRATION IN PEOPLE'S REPUBLIC OF CHINA: STRUCTURING OF ETHNIC MINORITIES
The paper examines the political processes in the People’s Republic of China associated with the forming of ethnic minorities’ participation in legislative and executive spheres.
T. P. Shiker
doaj
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Ethnic Studies Newsletter Vol. 4 No. 2
Seven page newsletter from the Ethnic Studies department dated December 1983. Newsletter is Volume 4, Number 2. Newsletter includes pieces on Dr. Benjamin P.
Ethnic Studies Department;
core +1 more source
008: FROM VIOLENT CONFLICT TO INSTITUTIONAL CONFLICT REGULATION
Constitutional treatment of cultural and territorial pluralism in the Republic of Macedonia followed the dynamic of ethnic conflict in this deeply divided society.
Zoran Ilievski
doaj
Seventy years of study on ethnic paleography in China
This paper systematically presents the development process of studying ancient Chinese ethnic scripts over the past seven decades since the founding of the People’s Republic of China in 1949, including the establishment of related research institutions ...
Jinbo Shi, Runhua Huang
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Ethnic Self-Esteem and Intergroup Attitudes Among the Estonian Majority and the non-Estonian Minority [PDF]
The study was focussed on the relationships between ethnic self-esteem and various indicators of intergroup attitudes in a representative sample of adult population of Estonia (N=1142).
Maaris Raudsepp
doaj
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

