Results 81 to 90 of about 334,473 (263)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The palliative and pernicious effects of racial system justification for the racially privileged and the racially oppressed

open access: yesFrontiers in Social Psychology
Systemic racism carries disparate and varying impacts for members of advantaged and disadvantaged racial groups, not only materially and socially, but also psychically, with consequences for psychological wellbeing.
Jeannine Alana Bertin   +2 more
doaj   +1 more source

Ethnic stereotypes in the field of intercultural interaction. Case Study: Republic of Tatarstan

open access: yesИсторическая этнология, 2018
The article presents the results of the field ethno-sociological research conducted in Kazan and the villages of the Republic of Tatarstan in 2017–2018, as part of an inter-regional study of the process of identifying Tatars in the Project of the State ...
Liliya V. Sagitova
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ethnocontact zones in system of ethnocultural division into districts of the North Caucasus

open access: yesНаука. Инновации. Технологии, 2022
The article describes the methodology, principles and taxonomic system ethnocultural of regionalization of the North Caucasus, characterized by ethnic and cultural identity of zoning with the inter-ethnic interaction within etnokontaktnyh zones.
Alexey Vladimirovitsh Lysenko   +2 more
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Analysis of Social Transformation in Ethnic Region Northwest China Under the Process of Ecology Restoration --Case Study on Jingyuan County,Ningxia

open access: yesShuitu baochi yanjiu, 2005
By discussing the effect of ecology restoration on regionel social development,Jingyuan county in south Ningxia Hui Nationality Autonomous Region,as sample to analyse the relation and interaction between ecology restoration and society transformation in ...
MA Hai-long~1, MI Wen-bao~
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

PSYCHOLOGICAL APPROACHES TO STUDY OF OPTIMAL MANAGEMENT ACTIVITIES IN LEADERS OF ETHNIC COMMUNITY ORGANIZATIONS

open access: yesRUDN Journal of Psychology and Pedagogics, 2015
The article describes the main psychological approaches, and in particular, the system-synergetic approach to the study of the management activities of the leaders of ethnic community organizations.
N T Kolesnik
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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