Results 71 to 80 of about 1,373,558 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

SYSTEM AND GENESIS OF ETHNIC DIASPORA CULTURE

open access: yesTHE BULLETIN, 2020
The problem of the historical formation of the culture of ethnic groups and the identification of their specific features is very urgent, since the diaspora culture is able to significantly transform depending on environmental conditions, among which socio-economic and ethnopolitical ones can become decisive. The result of transformational processes in
null Garifolla Yessim,   +2 more
openaire   +1 more source

Ethnic Coalitions of Convenience and Commitment: Political Parties and Party Systems in Kenya [PDF]

open access: yes
This paper analyzes the role of ethnicity in shaping the character of Kenya’s political parties and its party system since 1992. Drawing on a constructivist conception of ethnicity, it uses a framework of comparison derived from Donald Horowitz and ...
Sebastian Elischer
core  

Racial/Ethnic Differences in Cardiac Care: The Weight of the Evidence [PDF]

open access: yes, 2002
A substantial and growing body of research indicates that race/ethnicity -- independent of clinical and socioeconomic factors -- continues to matter in the U.S. health care system.

core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Multidimensional factors contributing to the dynamics of ethnic conflict in Ethiopia

open access: yesCogent Social Sciences
In Ethiopia, ethnic federalism was implemented in the 1990s with the intention of redressing past marginalization, in which certain groups were excluded from political participation, economic prospects, and cultural acknowledgement.
Keneni Jibat   +2 more
doaj   +1 more source

Inequalities and outcomes: end stage kidney disease in ethnic minorities

open access: yesBMC Nephrology, 2019
Background The international evidence about outcomes of End Stage Kidney Disease (ESKD) for ethnic minorities was reviewed to identify gaps and make recommendations for researchers and policy makers.
Emma Wilkinson   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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