Results 121 to 130 of about 1,373,558 (307)
Educational values, intrinsic or extrinsic : a study of parent pupil preferences : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Arts in Education at Massey University [PDF]
, 1975 A perennial problem faced by teachers, administrators and educational researchers is that of improving the performance levels of high school pupils. Efforts to understand some of the factors which contribute to scholastic achievement have established ...
Panny, Carol Constance
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The Successful Ghana Election of 2008: A Convenient Myth? Ethnicity in Ghana's elections revisited [PDF]
Ghana’s 2008 elections have been hailed by national and international observers as a model for Africa. This perception has prevailed despite persistent concerns about 'ethnic block voting' and electoral fraud. Electoral malpractice and vote rigging along
Jockers, Heinz +2 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The educational attainment of the second generation in Germany : social origins and ethnic inequality [PDF]
"With the German Microcensus we study the second generation's educational attainment in Germany focusing on the descendants of classic labour migrants. Our results show that educational outcomes in terms of attending or completing the highest schooling ...
Granato, Nadia, Kristen, Cornelia
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Migratory Movement: The Politics of Ethnic Community (Re) Construction Among Creoles of Color, 1920-1940 [PDF]
, 2005 This article considers the social and economic conditions under which Creoles of Color left the state of Louisiana from 1920-1940.1 Because Creoles in the years following 1920 were legally reclassified as black, many lost their land, social and legal ...
Jolivétte, Andrew
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Ethnicity and Party Systems in Francophone Sub-Saharan Africa [PDF]
Despite earlier assumptions that ethnicity is a central feature of African party systems, there is little substantial evidence for this claim. The few studies with an empirical foundation rarely rely on individual data and are biased in favor of ...
Alexander Stroh, Matthias Basedau
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source