Results 131 to 140 of about 24,665,452 (334)

Women of Color in the Private Sector: Their Employment in the Private Sector [PDF]

open access: yes, 2003
[Excerpt] This examination of the employment status of minority women or women of color relies primarily on the Equal Employment Opportunity Commission’s (EEOC’s) EEO-1 report.
U.S. Equal Employment Opportunity Commission
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Different Forms of Discrimination in the Criminal Justice System [PDF]

open access: yes, 2012
Focusing on discretion by the police, criminal justice practitioners and the courts at different stages in the criminal justice process, this chapter explores whether their judgements and decisions contribute to the overrepresentation of those from black,
Webster, CS
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

COMPARISONS OF HISPANIC HOUSEHOLDS' DEMAND FOR MEATS WITH OTHER ETHNIC GROUPS [PDF]

open access: yes
The objective of this research was to analyze the demand patterns of Hispanic households for meats in comparison with other ethnic groups using data from the 1998 Consumer Expenditure Survey.
Ames, Glenn C.W.   +2 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The educational attainment of the second generation in Germany : social origins and ethnic inequality [PDF]

open access: yes
"With the German Microcensus we study the second generation's educational attainment in Germany focusing on the descendants of classic labour migrants. Our results show that educational outcomes in terms of attending or completing the highest schooling ...
Granato, Nadia, Kristen, Cornelia
core  

The politicization of ethnic sentiments in Southern Thailand: The case of the Malay Muslims [PDF]

open access: yes, 2010
This study analyzes the politicization of ethnic sentiments in Thailand with particular focus on Southern Thailand. It is divided into six parts. The first part examines the relationship between the Thailand’s political system and the minority groups ...
Taya, Shamsuddin L.
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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