Results 171 to 180 of about 25,961,536 (353)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Ethnic and Fiscal Federalism in Nepal
, 2008 Nepal is in the process of making a democratic federal republic. We hope to contribute to the discussions of ethnic and fiscal federalism based on experiences from other countries.
Hatlebakk, Magnus, Aalen, Lovise
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
LIPID PEROXIDATION SYSTEM IN TYPE 1 DIABETES: ETHNIC ASPECTS
Acta Biomedica Scientifica, 2013 Oxidative stress is an acknowledged pathogenic mechanism in Type 1 diabetes mellitus. Acute increases in plasma glucose concentration may increase free radical production by the following mechanisms: labile glycation; auto-oxidation of glucose, and ...
L. I. Kolesnikova +5 more
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The Defence of Ethnic Identity in Malaysia
, 2010 The changing dynamics of interstate conflict in the post-Cold War environment led scholars to debate the relevance of established security theory. While traditionalists maintained that the state-centric theory should retain its primacy, others argued for
Jones-Leaning, Melanie
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Report No. 16: Study on the Social and Labour Market Integration of Ethnic Minorities [PDF]
Report for the High Level Advisory Group on Social and Labour Market Integration of Ethnic Minorities and the European Commission, Bonn 2008 (166 pages) [German version] (Studie über die soziale Eingliederung und Arbeitsmarktintegration ethnischer ...
Constant, Amelie F. +5 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Post-Socialist International Migration: The Case of China-to-South Korea Ethnic Labour Migration [PDF]
This paper examines an atypical south-north labour migration that emerged in the post-socialist international migration system: China-to-South Korea ethnic labour migration.
Kim, Anna Myunghee
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