Results 191 to 200 of about 17,961,033 (290)

Social marginalization and access to publicly funded home care in Ontario: a population-based retrospective cohort study. [PDF]

BMC Geriatr
Jabbar A, Babe G, Jones A, Vanstone M, Kuluski K, Heckman G, Costa AP.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The Gut Microbiota-Host Epigenetic Axis: An Emerging Biological Framework for Understanding Ethnic Disparities in Type 2 Diabetes Mellitus Susceptibility. [PDF]

Nutrients
Zaiou M.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Spatial and Temporal Disparities in Timely Hepatitis B Birth-Dose Vaccination in Chongqing, China, 2016-2025. [PDF]

Vaccines (Basel)
Xu B, Wan N, Wang Q, Bai N, Zhou C.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

An understanding of 'strengths' and 'strengths based practice' within older people from ethnic minorities in the UK. A qualitative systematic review. [PDF]

NIHR Open Res
Sobo-Allen L, Miller R, Bond L.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Barriers to and racial and ethnic differences in mental health care service utilization among staff in a large urban health care system. [PDF]

Psychol Serv
He C, Khan A, Klepser N, Buehler NJ, Doukas A, Ho S, Clark U, Mohamed NE, Pietrzak RH, Peccoralo L, Ripp J, DePierro J.   +11 more
europepmc   +1 more source