Results 71 to 80 of about 6,981 (181)

Triterpenoid Saponins from Tu Jia Ethnomedicine Bai San Qi and Their Cytotoxicity on Hep G2 and BGC-823 Cell Lines

open access: yesDigital Chinese Medicine, 2019
Objective: Tu Jia ethnomedicine is a unique medical system inherited and adhibited by Tu Jia minority living in central-south China. Panax japonicus C. A. Mey.
Li Wei   +7 more
doaj   +1 more source

Effective extraction of Xuetongsu and its role in preventing RA synovial hyperplasia by targeting synovial cell migration and apoptosis

open access: yesScientific Reports
Kadsura heteroclita (Roxb) Craib also named Xuetong in Tujia ethnomedicine in China, has been traditionally employed in rheumatoid arthritis (RA) treatment.
Yasi Deng   +13 more
doaj   +1 more source

PANoptosis-related genes in rheumatoid arthritis synovial tissue: screening, validation, and functional implications

open access: yesFrontiers in Immunology
ObjectiveTo screen and validate the expression of key PANoptosis-related genes in the synovial tissue of rheumatoid arthritis (RA) through bioinformatics approaches and in vitro/in vivo experiments, explore their role in RA synovial hyperplasia, and ...
Yunmi Lu   +15 more
doaj   +1 more source

Pharmacokinetic and Network Pharmacology Studies for the Prototype Components of Erigeron Breviscapus in Rat Model of Vascular Dementia Using UHPLC-Qtrap-MS/MS

open access: yesZhipu Xuebao
The whole dried plant of Erigeron breviscapus is clinically used in traditional Chinese medicine, and named as “Deng-Zhan-Xi-Xin”. The herb is primarily distributed in Yunnan, Guangxi, and Guizhou provinces of China, and its traditional therapeutic ...
Xue-meng GAO   +6 more
doaj   +1 more source

Cytisine N-methylene-(5,7,4′-trihydroxy)-isoflavone induces neural stem cell proliferation and reverses cognitive deficits in early Alzheimer’s disease models via canonical Wnt/β-catenin pathway

open access: yesFood Science and Human Wellness
Alzheimer’s disease (AD) is a degenerative disease of the central nervous system. It results in cognitive dysfunction due to the loss of functional neurons and a deficit of new neurons, which can lead to death in severe cases.
Yangyang Lu   +11 more
doaj   +1 more source

Growth Month-Associated Variation in Volatile Profiles, Anti-Glycation Capacity, and Antioxidant Activity of Cyclocarya paliurus Leaves: A Pilot Study

open access: yesFoods
Cyclocarya paliurus leaves, commonly consumed as “sweet tea”, remain underutilized after spring harvest. This pilot study investigated harvest month-associated changes in bioactivity-related properties and volatile profiles of mature leaves collected ...
Yanmeng Fu   +9 more
doaj   +1 more source

Xuetongsu attenuates bone destruction in rheumatoid arthritis by suppressing RANKL/RANK/NFATc1 pathway to inhibit osteoclastogenesis and bone resorption

open access: yesBone & Joint Research
Aims: Bone destruction is a pivotal pathological factor in the development of joint disability in rheumatoid arthritis (RA) patients, and there is a paucity of safe and effective drugs targeting bone destruction.
Hao Zheng   +11 more
doaj   +1 more source

Dendrobine alleviates CCl4-induced acute liver injury by inhibiting necroptosis through activation of the Nrf2/PPARγ/SOD2 signaling pathways

open access: yesChinese Medicine
Background Acute liver injury (ALI) represents a critical clinical challenge characterized by rapid degradation of hepatic function, necessitating prompt intervention for improved patient outcomes.
Yonggang Yang   +10 more
doaj   +1 more source

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