Development and validation of a Partial Least Squares-Discriminant Analysis (PLS-DA) model based on the determination of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) in hair for the diagnosis of chronic alcohol abuse [PDF]
The chronic intake of an excessive amount of alcohol is currently ascertained by determining the concentration of direct alcohol metabolites in the hair samples of the alleged abusers, including ethyl glucuronide (EtG) and, less frequently, fatty acid ethyl esters (FAEEs).
Eugenio Alladio +2 more
exaly +4 more sources
Body mass index (BMI) is a variable that complicates the interpretation of the alcohol metabolite ethyl glucuronide (EtG) in hair. However, direction on how EtG should currently be interpreted within individuals consuming moderate and excessive daily amounts of alcohol related to their BMI is lacking.
Crunelle, Cleo L +2 more
openaire +5 more sources
Determinação de etil-glicuronídeo e etil-sulfato em sangue por UPLC-MS/MS: aplicação clínica em vítimas de trauma [PDF]
We developed a UPLC-MS/MS method for the quantification of the ethanol metabolites ethyl-glucuronide (EtG) and ethyl-sulfate (EtS) in blood samples. Sample preparation was a protein precipitation with acetonitrile 0.1% formic acid containing internal ...
Isabela Ritter Ott +5 more
doaj +1 more source
Urinary alcohol and ethyl glucuronide as a screening tool for alcohol use in pregnancy: A multicenter prospective study. [PDF]
In this objective, anonymous study of 1053 women attending their first antenatal appointment, a surprisingly low percentage (0.38%) contained ethyl glucuronide (EtG), a metabolite of alcohol. These findings challenge previous studies that suggest that up to 60% of pregnant women in Ireland consume alcohol during pregnancy. Abstract Introduction Reports
McCormick CA +10 more
europepmc +2 more sources
Ethyl Glucuronide in Hair: A 10-Year Overview. [PDF]
The present study builds on a unique collection of more than 68,000 hair EtG results collected in the Northen Italy between 2013 and 2022. We investigated trends in alcohol consumption in terms of age, gender, recidivism, applicants, sampling region, sampling length, across seasons, and the COVID‐19.
Casati S +8 more
europepmc +2 more sources
Ethyl Glucuronide, Ethyl Sulfate and Acetone as Biomarkers for Alcohol Based Hand Sanitizers Chronic Exposure in Health Care Workers [PDF]
Introduction: health care workers (HCWs) are exposed to alcohols during hand antisepsis by both dermal contact and inhalation. This study aimed to assess the ethanol and isopropanol (ISOP) absorption in HCWs due to alcohol based hand sanitizers ...
Dina El-rafey, Ghada Mansour
doaj +1 more source
Ethyl glucuronide (EtG) is a non-volatile, non-oxidative, hydrophilic, and stable ethanol phase II metabolite. EtG is produced through ethanol glucuronidation by UDP-glucuronosyltransferase (UGT), a phase II enzyme.
Valentina Triolo +10 more
doaj +1 more source
Integrating Phosphatidylethanol to Enhance Alcohol Quantification in Steatotic Liver Disease and Clinical Trials. [PDF]
ABSTRACT Accurate quantification of alcohol intake is essential for the diagnosis, subclassification, and management of steatotic liver disease (SLD). In everyday clinical practice, alcohol histories rely primarily on physician‐assisted self‐report, with validated questionnaires used variably.
Rady ED, Cotter TG.
europepmc +2 more sources
Urinary ethyl glucuronide (EtG), an alcohol biomarker, plays an essential role in monitoring alcohol abstinence and relapse during treatment for alcohol dependence.
Shayani Ghosh +5 more
doaj +1 more source
Secondary analysis of a combined harm-reduction treatment and extended-release naltrexone randomized clinical trial for alcohol use disorder: Differences across race, ethnicity and sex assigned at birth. [PDF]
Abstract Background and Aims In a prior randomized clinical trial (RCT), combined pharmacobehavioral harm‐reduction treatment improved alcohol outcomes and physical health‐related quality of life (PH‐QoL). In this secondary analysis, we tested race, ethnicity and sex assigned at birth as predictors and moderators of these effects.
Goldstein SC +4 more
europepmc +2 more sources

