Results 1 to 10 of about 2,761 (156)

Impact of Smear Layer Removal Using Etidronate- and EDTA-Based Irrigation Protocols on Root Canal Microbiota: An In Vivo Study [PDF]

Dentistry Journal
Background: The effective elimination of root canal microbiota is essential for the treatment of apical periodontitis. The smear layer formed during instrumentation limits the penetration of irrigants into dentinal tubules, making chelation a critical ...
Svetlana Razumova, Anzhela Brago, Anzhelika Kryuchkova, Zilolakhon Khakimova, Nazira Khabibova, Alexander Volkov, Haydar Barakat, Natalya Dikopova   +7 more
doaj   +2 more sources

Evaluation of the efficiency of smear layer removal during endodontic treatment using scanning electron microscopy: an in vitro study [PDF]

BMC Oral Health
Background The smear layer formed during root canal instrumentation negatively affects root canal irrigation activity, which in turn can affect the treatment prognosis of endodontic treatment.
Svetlana Razumova, Anzhela Brago, Anzhelika Kryuchkova, Vasiliy Troitskiy, Ruzanna Bragunova, Haydar Barakat   +5 more
doaj   +2 more sources

Efficacy of Continuous Chelation With Etidronate And Sequential Chelation With Chitosan On Bacterial Reduction In Teeth With Pulp Necrosis: A Double-Blind, Randomized Clinical Trial [PDF]

European Endodontic Journal
Objective: This study compared the efficacy of continuous chelation with etidronate and sequential chelation with chitosan to traditional chelation with EDTA in reducing bacterial levels in teeth with necrotic pulp.
Karthikeyan Anbalagan, Amit Jena, Luna Samanta, Akhil Changanath, Anwesha Pradhan, Govind Shashirekha, Vinay Shivagnage   +6 more
doaj   +2 more sources

The TEMP-PREVENT trial: a study protocol for a randomized, double-blind, placebo-controlled clinical trial of etidronate for treatment in young adult patients with pseudoxanthoma elasticum [PDF]

Trials
Background Pseudoxanthoma elasticum (PXE) is a genetic disease with autosomal recessive inheritance, characterized by slowly progressive ectopic calcification in the elastic fibers of the skin, Bruch’s membrane in the retina, and in the arteries ...
Iris M. Harmsen, Melanie Haverkamp, Tim C. van den Beukel, Madeleine Kok, Pim A. de Jong, Evelien van Valen, Redmer van Leeuwen, Jeannette Ossewaarde-van Norel, Wilko Spiering   +8 more
doaj   +2 more sources

Calcium Phosphate/Etidronate Disodium Biocement: Etidronate, Retarder or Accelerator [PDF]

Nano Biomedicine and Engineering, 2014
Bisphosphonate release from calcium phosphate cement has been investigated. We hypothesized that local delivery of bisphosphonate from the calcium phosphate cement improves the mechanical properties.
Nasim Nosoudi, Amin Hasanzadeh, Drew Holman, Sayed Mahmood Rabiee, Saeed Hesaraki, Fatollah Moztarzadeh, Michael Gelinsky   +6 more
doaj   +2 more sources

The effects of etidronate on brain calcifications in Fahr’s disease or syndrome: rationale and design of the randomised, placebo-controlled, double-blind CALCIFADE trial [PDF]

Orphanet Journal of Rare Diseases
Background Fahr’s disease and syndrome are rare disorders leading to calcification of the small arteries in the basal ganglia of the brain, resulting in a wide range of symptoms comprising cognitive decline, movement disorders and neuropsychiatric ...
Birgitta MG Snijders, Gini Mathijssen, Mike JL Peters, Marielle H Emmelot-Vonk, Pim A de Jong, Susan Bakker, Heleen A Crommelin, Ynte M Ruigrok, Eva H Brilstra, Vera PM Schepers, Wilko Spiering, Evelien van Valen, Huiberdina L Koek   +12 more
doaj   +2 more sources

Case report: Osteomalacia due to bisphosphonate treatment in a patient on hemodialysis

BMC Nephrology, 2021
Background No publications have reported on osteomalacia in patients receiving intermittent cyclical therapy with etidronate (a bisphosphonate) and undergoing long-term hemodialysis (HD). Case presentation We report on a 46-year-old Japanese man admitted
Masaki Hatano, Izuru Kitajima, Seizo Yamamoto, Masaki Nakamura, Kazuya Isawa, Yutaka Hirota, Junichi Hoshino, Naoki Sawa, Yoshifumi Ubara   +8 more
doaj   +1 more source

The Abcc6a Knockout Zebrafish Model as a Novel Tool for Drug Screening for Pseudoxanthoma Elasticum

Frontiers in Pharmacology, 2022
Pseudoxanthoma elasticum (PXE) is a multisystem ectopic mineralization disorder caused by pathogenic variants in the ABCC6 gene. Though complications of the disease can be treated, PXE itself remains currently intractable.
M. Van Gils, M. Van Gils, A. Willaert, A. Willaert, P. J. Coucke, P. J. Coucke, O. M. Vanakker, O. M. Vanakker   +7 more
doaj   +1 more source

History of etidronate

Bone, 2020
Etidronate is a non-nitrogen-containing bisphosphonate. Because it binds with calcium and inhibits crystal formation and dissolution, it was considered by Procter & Gamble as an additive to toothpaste (to prevent build-up of tartar) and detergent (to bind calcium and increase sudsing in "hard" water).
Nelson B. Watts, Charles H. Chesnut, Harry K. Genant, Steven T. Harris, Rebecca D. Jackson, Angelo A. Licata, Paul D. Miller, W. Jerry Mysiw, Bradford Richmond, David Valent   +9 more
openaire   +4 more sources

Comparative Evaluation of the Effect of Different Chelating Agents on Mineral Content and Erosion of Radicular Dentine: A FESEM-EDS Analysis

European Endodontic Journal, 2023
Objective: Irrigating solutions play an important role in the debridement and disinfection of the root canal space, and thus, it is crucial to comprehend their effects on the composition and surface structure of radicular dentine.
Nishad Kadulkar, Rubi Kataki, Adrija Deka, Himchumi Medhi, Suchismita Chakraborty, Abhishek Singh   +5 more
doaj   +1 more source