Results 11 to 20 of about 3,485 (208)
The effect of etidronate on choroidal neovascular activity in patients with pseudoxanthoma elasticum. [PDF]
PLoS ONE, 2020 AimTo assess the effect of the bisphosphonate etidronate on choroidal neovascular (CNV) activity in patients with pseudoxanthoma elasticum (PXE).MethodsThis is an ancillary study in a single center, randomized, double-blind placebo-controlled trial (RCT)
Sara Risseeuw +6 more
doaj +2 more sources
Indian Journal of Health Sciences and Biomedical Research KLEU, 2016 Objective: Bisphosphonates represent the first choice in the treatment of osteoporosis, and no data are available concerning their effects on comorbid behavior alterations.
N Amitha, S S Torgal
doaj +2 more sources
Therapeutics and Clinical Risk Management, 2011 Jun Iwamoto1, Yoshihiro Sato2, Mitsuyoshi Uzawa3, Tsuyoshi Takeda1, Hideo Matsumoto11Institute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo, Japan; 2Department of Neurology, Mitate Hospital, Fukuoka, Japan; 3Department of ...
Iwamoto J +4 more
doaj +1 more source
Türk Osteoporoz Dergisi, 2005 Osteogenesis imperfecta(OI) is a kongenital skelatal disorder charecterized by low bone mass and increased bone fragility. Fractures due to increased bone fragility occur frequently in childhood and decrease with age.
Cengiz Bahadır +2 more
doaj +1 more source
Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast. [PDF]
Aust Endod JABSTRACT Etidronic acid (HEBP) causes fewer alterations in dentine and can be used mixed with sodium hypochlorite during root canal preparation. This study investigated the cytotoxicity effects of the HEDP and EDTA on human periodontal ligament fibroblast cells. Primary culture was established from human periodontal ligament tissue of one donor and was
de Almeida BVN +6 more
europepmc +2 more sources
Cyclical Etidronate Reduces the Progression of Arterial Calcifications in Patients with Pseudoxanthoma Elasticum: A 6-Year Prospective Observational Study. [PDF]
J Clin MedBackground: Pseudoxanthoma elasticum (PXE), a rare genetic disorder presenting with slowly progressing calcification of various tissues, including the arteries, is caused by mutations in the ABCC6 gene that lead to the reduction of pyrophosphate, a ...
Harmsen IM +6 more
europepmc +4 more sources
A comprehensive approach to the in vitro and in vivo study of a preparation containing etidronate of lanthanide and calcium ions [PDF]
Гений oртопедии, 2019 The search for new more effective techniques to repair bone fractures and defects is an urgent task of healthcare. Objective To explore the efficacy of a preparation containing etidronates of lanthanide and calcium ions in regenerative repair of bone ...
Sergei V. Boichuk +7 more
doaj +1 more source
Upper gastrointestinal adverse events and cyclical etidronate.
, 1997 PURPOSE: Recently, there have been several published case reports of esophagitis associated with the use of aminobisphosphonates. The objective of this study was to evaluate the upper gastrointestinal (GI) safety of cyclical etidronate, an ...
Van Staa, Tjeerd; id_orcid +3 more
core +3 more sources
Drug Repurposing for Rare Diseases: A Role for Academia
Frontiers in Pharmacology, 2021 Background: The European Commission highlights in its Pharmaceutical Strategy the role of academic researchers in drug repurposing, especially in the development of orphan medicinal products (OMPs). This study summarizes the contribution of academia over
Sibren van den Berg +5 more
doaj +1 more source
Etidronate as A Weak Chelating Agent on Root Canal Dentin: An Update Review [PDF]
Journal of Clinical and Diagnostic Research, 2017 Successful root canal treatment depends on proper biomechanical cleaning and shaping of root canal system followed by threedimensional obturation. Irrigation solutions and chelating agents are used during root canal treatment to assist in smear layer ...
Samah Samir Bedir +2 more
doaj +1 more source