Results 21 to 30 of about 3,485 (208)

Effect of Preparations Based on Lanthanide Ions and Calcium on the Bone Density in Rats with a Femur Fracture

Travmatologiâ i Ortopediâ Rossii, 2020
Purpose of the study — to evaluate bone density at the femur fracture site with local introduction of preparations based on etidronate lanthanide ions and calcium in the experiment. Materials and Methods. The experiment included 45 male rats divided into
I. F. Akhtyamov, F. V. Shakirova, D. A. Korobeynikova, Han Hao Zhi, R. I. Sadykov   +4 more
doaj   +1 more source

Skeletal abnormalities secondary to antenatal etidronate treatment for suspected generalised arterial calcification of infancy

Bone Reports, 2020
Background: Generalised arterial calcification of infancy (GACI) is a rare disorder characterised by the deposition of hydroxyapatite crystals within the vessel walls. It is associated with a high mortality rate.
Neha Agarwal, Umber Agarwal, Zarko Alfirevic, Joyce Lim, Musa Kaleem, Caren Landes, M. Zulf Mughal, R. Ramakrishnan   +7 more
doaj   +1 more source

Treatment of arterial calcification in patients with chronic limb threatening ischemia with etidronate: protocol of an investigator-initiated multicenter, double blind, placebo-controlled, randomized clinical trial

CVIR Endovascular, 2022
Background Pathologic studies have shown that in patients with critical limb threatening ischaemia (CLTI) medial arterial calcifications are frequently found and may be responsible for aggravating the disease.
R. Hoogervorst, H. van Overhagen, P. A. de Jong, W. Spiering, G. J. de Borst, H. T. C. Veger, A. T. A. Mairuhu, W. P. T. M. Mali   +7 more
doaj   +1 more source

Comparison of Ultrasonic and Laser-activated Continuous Chelation Irrigation on Postoperative Pain after Primary Endodontic Therapy: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Irrigation solutions are used to flush away debris, remove the smear layer, and disinfect the non instrumented areas of the root canal system.
Vinaya Pisal, Deebah Choudhary, Ajay Singh Rao, Nimisha Shah, Devashree Darak, Chandni Shah, Sejal Dodal, Rutvi Karande   +7 more
doaj   +1 more source

Preparation of mixed trialkyl alkylcarbonate derivatives of etidronic acid via an unusual route

Beilstein Journal of Organic Chemistry, 2012
A method to prepare four (3a–d) trialkyl alkylcarbonate esters of etidronate from P,P'-dimethyl etidronate and alkyl chloroformate was developed by utilizing unexpected demethylation and decarboxylation reactions.
Petri A. Turhanen, Janne Weisell, Jouko J. Vepsäläinen   +2 more
doaj   +1 more source

Vascular Effects of Bisphosphonates–-A Systematic Review

Clinical Medicine Insights: Endocrinology and Diabetes, 2012
Background Osteoporosis and cardiovascular disease are interconnected entities with pathophysiological similarities. Bisphosphonates are therapeutic options available for resorptive bone diseases; however, experimental evidence has demonstrated a role ...
Leyna L. Santos, Taciana B. Cavalcanti, Francisco A. Bandeira   +2 more
doaj   +1 more source

Protective Effect of Phytic Acid in Cardiovascular Diseases: A Systematic Review

ChemFoodChem, EarlyView.
ABSTRACT Cardiovascular diseases (CVDs) are a cluster of ailments that impact the heart and blood vessels and are a primary public health problem of mortality on a global scale. Phytic acid, a dietary constituent frequently present in foods like seeds, has been linked to many pharmacological attributes, including anti‐cancer, antioxidant, anti ...
Marta M. S. de Freitas Almeida, Éverton A. Pereira, Patricia Severino, Cristina Blanco‐Llamero, Sandra L. Santos, Luciana N. Andrade, Ricardo G. Amaral, Eliana B. Souto   +7 more
wiley   +1 more source

Mind the Gap: Predictors of Osteoporosis Treatment Following Fragility Fracture in Parkinsonism

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Fracture risk is increased in Parkinson's yet this risk is often not addressed. Objectives Our objective was to study the extent to which osteoporosis was treated, and predictors of treatment in a large representative cohort with parkinsonism.
Katie C. Naylor, Emily J. Henderson, Emma Tenison   +2 more
wiley   +1 more source

Dose-dependent absorption of disodium etidronate

, 1985
The gastrointestinal absorption of disodium etidronate (as [14C]disodium etidronate) was investigated in the rat proximal jejunum in-situ. Studies using various initial concentrations of the drug suggested that etidronate absorption occurred by passive ...
Richard P Gural, Vinod S Chungi, Lewis W Dittert, Robert P Shrewsbury   +3 more
core   +1 more source

Acute effects of etidronate on glucocorticoid-induced bone degradation [PDF]

, 2000
OBJECTIVES: To study the acute short-term effects on the biochemical parameters of calcium and bone homeostasis in post-menopausal women treated with a high dose of prednisone alone or with additional etidronate, before and ...
Struijs, A. (Ard), Smals, A.G.H., Struijs, A., Hackeng, W.H.L., Mulder, H., Witte, S.A. de, Hackeng, W.H., Mulder, H. (Hans), Smals, A.   +8 more
core   +1 more source