Results 71 to 80 of about 1,956,484 (356)

Practice Recommendations for Genetic Testing of Ataxias

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan, Amy D. Mook, Michelle Rochman, Jin Yun Helen Chen, Weiyi Mu, George R. Wilmot, Liana S. Rosenthal, Wendy R. Uhlmann   +7 more
wiley   +1 more source

First identification and isolation of equine herpesvirus type 1 in aborted fetal lung tissues of donkeys

Virology Journal
Background Equine herpesvirus type 1 (EHV-1) is commonly associated with horse abortion. Currently, there are no reported cases of abortion resulting from EHV-1 infection in donkeys. Results This was the first survey-based study of Chinese donkeys.
Panpan Tong, Juanjuan Pan, Yueyi Dang, Enhui Yang, Chenyang Jia, Ruli Duan, Shuyao Tian, Nuerlan Palidan, Ling Kuang, Chuanfeng Wang, Gang Lu, Jinxin Xie   +11 more
doaj   +1 more source

Mortality Trends of Stomach Cancer in Qidong City, 1972—2016

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate the mortality trends of stomach cancer from 1972 to 2016 in Qidong, Jiangsu Province. Methods We collected and analyzed the mortality of stomach cancer in Qidong from 1972 to 2016 by gender and age from the cancer registry data ...
DING Lulu, ZHU Jian, ZHANG Yonghui, CHEN Yongsheng, WANG Jun, CHEN Jianguo   +5 more
doaj   +1 more source

Hepatocellular Carcinoma Survival by Etiology: A SEER‐Medicare Database Analysis

Hepatology Communications, 2020
In the United States, hepatocellular carcinoma (HCC) survival varies with tumor characteristics, patient comorbidities, and treatment. The effect of HCC etiology on survival is less clearly defined. The relationship between HCC etiology and mortality was
G. Brar, T. Greten, B. Graubard, T. McNeel, J. Petrick, K. McGlynn, S. Altekruse   +6 more
semanticscholar   +1 more source

A study of the etiology of referred Otalgia [PDF]

, 2012
Introduction: Otalgia is one of the complaints which may occur at any age. The etiology of the pain may be in the ear, structures around the ear or other head and neck structures.
Behnampour, N., Taziki, M.H.
core   +1 more source

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source

The etiology of Bell’s palsy: a review

Journal of Neurology, 2019
Bell’s palsy is the most common condition involving a rapid and unilateral onset of peripheral paresis/paralysis of the seventh cranial nerve. It affects 11.5–53.3 per 100,000 individuals a year across different populations.
Wenjuan Zhang, Lei Xu, Tingting Luo, Feng Wu, Bin Zhao, Xianqi Li   +5 more
semanticscholar   +1 more source

Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk. [PDF]

, 2019
BackgroundThe development of an autistic brain is a highly complex process as evident from the involvement of various genetic and non-genetic factors in the etiology of the autism spectrum disorder (ASD). Despite being a multifactorial neurodevelopmental
Gu, Ran, Ji, Yu, Kumar, Santosh, Rai, Sunil, Reynolds, Kurt, Zhou, Chengji J   +5 more
core  

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague, Kristin Engelstad, Yue Ge, Amber Tucker, Shufang Li, Jasim Uddin, Ziwei Zhao, John L. P. Thompson, Michio Hirano   +8 more
wiley   +1 more source

Joint analysis of lncRNA m6A methylome and lncRNA/mRNA expression profiles in gastric cancer

Cancer Cell International, 2020
Background N 6-methyladenosine (m6A) modification might be closely associated with the genesis and development of gastric cancer (GC). Currently, the evidence established by high-throughput assay for GC-related m6A patterns based on long non-coding RNAs (
Zhi Lv, Liping Sun, Qian Xu, Chengzhong Xing, Yuan Yuan   +4 more
doaj   +1 more source