Results 51 to 60 of about 968,008 (318)

Correlation between negative expression of pepsinogen C and a series of phenotypic markers of gastric cancer in different gastric diseases

open access: yesCancer Medicine, 2018
Gastric tumorigenesis is a multistep process initiated by chronic superficial gastritis (SG), followed by atrophic gastritis (AG), then intestinal metaplasia (IM), and finally by dysplasia and adenocarcinoma according to the Correa model.
Jingyi Jiang   +6 more
doaj   +1 more source

Mucosa-Associated Microbiota in Gastric Cancer Tissues Compared With Non-cancer Tissues

open access: yesFrontiers in Microbiology, 2019
The link between microbiota and gastric cancer (GC) has attracted widespread attention. However, the phylogenetic profiles of niche-specific microbiota in the tumor microenvironment is still unclear.
Xiao-Hui Chen   +14 more
doaj   +1 more source

ETIOLOGY OF DYSENTERY. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1901
Our imperfect knowledge of the nature of dysentery is not due to lack of opportunity for, or of energy in, its study. The disease, in the past quarter of a century, has not escaped the attention of bacteriologists, although it must be confessed that the results of somewhat extensive studies along these lines have been far less conclusive than might ...
openaire   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Identification of differential proteomics in Epstein-Barr virus-associated gastric cancer and related functional analysis

open access: yesCancer Cell International, 2021
Background Epstein-Barr virus-associated gastric cancer (EBVaGC) is the most common EBV-related malignancy. A comprehensive research for the protein expression patterns in EBVaGC established by high-throughput assay remains lacking. In the present study,
Zeyang Wang   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Mucin phenotype-based deep learning framework for intestinal metaplasia-carcinogenesis progression prediction

open access: yesnpj Precision Oncology
This study decodes spatiotemporal mucin dynamics in gastric carcinogenesis, revealing gastric-type markers (MUC5AC/MUC6) decline progressively while intestinal-type markers (MUC2/CD10) peak in gastric intestinal metaplasia (GIM) before decreasing in ...
Xiaoyang Wu   +13 more
doaj   +1 more source

Serum levels of matrix metalloproteinase 9 and toll-like receptor 4 in acute aortic dissection: a case-control study

open access: yesBMC Cardiovascular Disorders, 2018
Background Matrix metalloproteinase 9 (MMP9) and Toll-like receptor 4 (TLR4) play important roles in aortic pathophysiology. However, there is lacking research on serum TLR4 levels in acute aortic dissection (AAD) patients, and the performance of serum ...
Tan Li   +6 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Relevance of Biofilm Models in Periodontal Research: From Static to Dynamic Systems

open access: yesMicroorganisms, 2021
Microbial biofilm modeling has improved in sophistication and scope, although only a limited number of standardized protocols are available. This review presents an example of a biofilm model, along with its evolution and application in studying ...
María Carmen Sánchez   +5 more
doaj   +1 more source

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