Results 71 to 80 of about 889,444 (319)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Virology JournalBackground Equine herpesvirus type 1 (EHV-1) is commonly associated with horse abortion. Currently, there are no reported cases of abortion resulting from EHV-1 infection in donkeys. Results This was the first survey-based study of Chinese donkeys.
Panpan Tong +11 more
doaj +1 more source
BMC Cardiovascular Disorders, 2018 Background Matrix metalloproteinase 9 (MMP9) and Toll-like receptor 4 (TLR4) play important roles in aortic pathophysiology. However, there is lacking research on serum TLR4 levels in acute aortic dissection (AAD) patients, and the performance of serum ...
Tan Li +6 more
doaj +1 more source
Relevance of Biofilm Models in Periodontal Research: From Static to Dynamic Systems
Microorganisms, 2021 Microbial biofilm modeling has improved in sophistication and scope, although only a limited number of standardized protocols are available. This review presents an example of a biofilm model, along with its evolution and application in studying ...
María Carmen Sánchez +5 more
doaj +1 more source
THE ETIOLOGY OF CHOROIDITIS. [PDF]
JAMA: The Journal of the American Medical Association, 1905 The following observations regarding the causal relations of choroiditis with rubeola are the results of observations of numerous cases of this disease which have come under my observation. It has always seemed to the writer that the pathology of choroiditis has not been so definitely established or defined as to enable the practitioner to feel that he
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Joint analysis of lncRNA m6A methylome and lncRNA/mRNA expression profiles in gastric cancer
Cancer Cell International, 2020 Background N 6-methyladenosine (m6A) modification might be closely associated with the genesis and development of gastric cancer (GC). Currently, the evidence established by high-throughput assay for GC-related m6A patterns based on long non-coding RNAs (
Zhi Lv +4 more
doaj +1 more source
ETIOLOGY OF PERICARDITIS. [PDF]
JAMA: The Journal of the American Medical Association, 1901 The etiology of pericarditis has been discussed so often and by so many that it is indeed difficult to present a discussion of it to a body of this character in such a manner as to arouse interest. For this reason it seemed better to disregard the extensive literature upon this subject and utilize the reports of three hundred cases as a text, dwelling ...
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Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source