Results 81 to 90 of about 13,978 (200)

Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4836-4854, August 2026.
Background and Purpose Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.
Jinrui Lyu, Rajasekar Nagarajan, Dishary Sharmin, Prithu Mondal, Maltesh Kambali, Muxiao Wang, Jinyan Zhou, Makoto Inoue, James M. Cook, Uwe Rudolph   +9 more
wiley   +1 more source

Magnesium sulfate versus Lidocaine pretreatment for prevention of pain on etomidate injection: A randomized, double-blinded placebo controlled trial

Journal of Research in Pharmacy Practice, 2015
Objective: Etomidate is an imidazole derivative and formulated in 35% propylene glycol. When given without a rapid lidocaine injection, etomidate is associated with pain after injection.
Mohammadreza Safavi, Azim Honarmand, Ashraf Sadat Sahafi, Seyyed Mohammad Sahafi, Mohammadali Attari, Mahsa Payandeh, Alireza Iazdani, Nilofarsaddat Norian   +7 more
doaj   +1 more source

Pre‐anaesthetic risk assessment and management of dogs with myxomatous mitral valve disease: a spectrum of care narrative review

Journal of Small Animal Practice, Volume 67, Issue 8, Page 663-679, August 2026.
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon, L. Köster, E. Vettorato, A. H. Estrada   +3 more
wiley   +1 more source

Role of extracorporeal membrane oxygenation in the management of myocarditis during caesarean birth

Anaesthesia Reports, Volume 14, Issue 2, July‐December 2026.
Summary We describe a pregnant patient who presented in labour with diffuse ST‐segment elevation on electrocardiography and biochemical evidence of myocardial injury. Transthoracic echocardiography showed severe biventricular dysfunction. An urgent caesarean birth was indicated due to breech presentation and severe cardiac dysfunction.
Y. Hasan, A. Engdahl, F. Kromah, A. Karuppiah   +3 more
wiley   +1 more source

Clinical and Molecular Pharmacology of Etomidate

, 2011
This review focuses on the unique clinical and molecular pharmacologic features of etomidate. Among general anesthesia induction drugs, etomidate is the only imidazole, and it has the most favorable therapeutic index for single-bolus administration.
Stuart A. Forman, David S. Warner
core   +1 more source

DRUG INTERACTION BETWEEN IVERMECTIN AND ETOMIDATE: INVESTIGATION ON THE EFFECT OF IVERMECTIN ON ETOMIDATE ANAESTHESIA

, 2020
The present study aims to determine the effect of ivermectin on the duration of anaesthesia performed with etomidate and to find out if there are any interactions between these two drugs at the central nervous system level.
Türel, İ., Yilmaz, O., Öner, A.C., Yücel, U.M.   +3 more
core   +1 more source

Comparing the Effect of Sodium Thiopental, Magnesium Sulfate, Midazolam, Prime Etomidate, and Remifentanil on Myoclonus Incidence and Pain Induced by Anesthesia with Etomidate

مجله دانشکده پزشکی اصفهان, 2018
Background: This study aimed to compare premedication with sodium thiopental, magnesium sulfate, midazolam, prime etomidate dosage, remifentanil, and normal saline on decreasing myoclonus incidence and pain induced by anesthesia with etomidate. Methods:
Mohammadreza Safavi, Azim Honarmand, Shahrbanoo Zolfaghari   +2 more
doaj   +1 more source

Hemodynamic Changes following Anesthesia Induction and LMA Insertion with Propofol, Etomidate, and Propofol + Etomidate [PDF]

, 2013
Introduction: LMA is a simple supra-laryngeal device which is used to establish and maintain airway. Despite the common use of the LMA, there are no optimal methods for induction of anesthesia that can guarantee a proper insertion.
Samad EJ Golzari, Marjan Dehdilani, Effat Torabi, Hamzeh Hosseinzadeh   +3 more
core   +2 more sources

Underlying Mechanisms of Memory Deficits Induced by Etomidate Anesthesia in Aged Rat Model: Critical Role of Immediate Early Genes

Chinese Medical Journal, 2016
Background: Etomidate (R-1-[1-ethylphenyl] imidazole-5-ethyl ester) is a widely used anesthetic drug that had been reported to contribute to cognitive deficits after general surgery. However, its underlying mechanisms have not been fully elucidated.
Xu Li, Fen Lu, Wei Li, Jun Xu, Xiao-Jing Sun, Ling-Zhi Qin, Qian-Lin Zhang, Yong Yao, Qing-Kai Yu, Xin-Liang Liang   +9 more
doaj   +1 more source

Chinese Society of Pediatric Anesthesiology Guideline for Pediatric Sedation (2025)

Pediatric Anesthesia, Volume 36, Issue 7, Page 850-871, July 2026.
ABSTRACT Background With the increasing variety of pediatric diagnostic procedures, a growing number of children require sedation for diagnostic examinations. Appropriate sedation protocols guarantee the safety of children during sedation and improve its efficiency.
Xingrong Song, Dongxu Lei, Yu Cui, Zhen Du, Yingping Jia, Yue Jin, Hang Tian, Ying Xu, Lifang Yang, Jianmin Zhang, Jijian Zheng, Yunxia Zuo, Liang Zhong, John Zhong, Maryrose Osazuwa, Elizabeth Drum, Charles Dean Kurth, Yue Huang, Qinghua Huang, Heqi Liu, Wei Liu, Rui Ma, Dongpi Wang, Tingting Wang, Zixin Wang, Siwei Wei, Lei Yang, Rui Zhou, Liumei Chen, Weifeng Yu, Jun Li, Mazhong Zhang, Li Zhang, Shuangquan Qu, Shoudong Pan, Rong Wei, Liming Cheng, Yaolong Chen, Xueping Li, Zhenyu Tang   +39 more
wiley   +1 more source