Results 171 to 180 of about 780,603 (289)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A user-driven consent platform for health data sharing in digital health applications. [PDF]

NPJ Digit Med
Brückner S, Dridi A, Deshmukh A, Kirsten T, Lauber-Rönsberg A, Riedel R, Hetmank S, Welzel C, Gilbert S.   +8 more
europepmc   +1 more source

Advanced materials to enhance the nuclear performances of the high temperature Dual Coolant Lithium lead breeding blanket for the EU DEMO

Nuclear Materials and Energy
David Sosa, Iole Palermo, I. Fernández-Berceruelo, J. Alguacil, Juan Pablo Catalán, Maria Gonzalez, J. Patiño   +6 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Simple, fast, reliable: multiplex digital PCR quantification of 19 genetically modified soybean events. [PDF]

GM Crops Food
Jelenčič A, Štebih D, Demšar T, Dobnik D.   +3 more
europepmc   +1 more source

3D modelling of the R&W TF coil design for EU-DEMO including the winding pack and frictional effects

Cryogenics (Guildford)
R. Ortwein, X. Sarasola, Federica Damatte   +2 more
semanticscholar   +1 more source

Implementation of the EU-DEMO Exhaust Modelling Roadmap

, 2022
Wiesen, S, Aho-Mantila, L, Dasbach, S, Matveev, D, Romazanov, J, Wischmeier, M, Osawa, R, Subba, F:, Coleman, M, Maviglia, F, Siccinio, M, Zohm, H, Bernert, M, Brezinsek, S   +13 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comparative synthesis of sociocultural and political influences (SPIs) on COVID-19 vaccine hesitancy: an interdisciplinary systematic review. [PDF]

BMC Public Health
Ma K, Christensen M, Turnbull M.
europepmc   +1 more source

EU DEMO pulsating balance of plant: Power conversion system operated with no thermal energy storage

Fusion engineering and design
Andrea Burlando, L. Barucca, Alessio D’Alessandro, Alberto Traverso, Carlo Bima, Marco Mantero   +5 more
semanticscholar   +1 more source