Results 161 to 170 of about 6,819,719 (259)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Notable trends in the EU budget [PDF]

The European Union budget has a number of specific characteristics which make it different from the budgets of the Member States : in principle, it must never be in deficit, and there is a special decision-making procedure.
H. Geeroms, P. Butzen, E. De Prest
core  

Exploring the Drivers of Food Waste Across EU Member States: A Socio-Economic and Environmental Perspective. [PDF]

Foods
Aleksanyan V, Arion FH, Gevorgyan S, Markosyan D, Parsyan SH, Mnacakanyan K, Oroian FC, Muresan IC, Arion ID, Chis S.   +9 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Economic and monetary integration of the new Member States - helping to chart the route [PDF]

This paper examines diverse aspects of the monetary integration of the ten new Member States (NMS) which joined the EU on 1 May 2004 into the euro area.
Michael Flad, Ignazio Angeloni, Francesco Paolo Mongelli   +2 more
core  

Relation of changes in productivity and remuneration of the labor factor in agriculture in EU Member States. [PDF]

PLoS One
Floriańczyk ZJ, Rembisz W, Pawłowska A.   +2 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Current status of radiologist staffing, education and training in the 27 EU Member States. [PDF]

Insights Imaging
Brady AP, Paulo G, Brkljacic B, Loewe C, Szucsich M, Hierath M, European Society of Radiology.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Perspectives on the impact of regulatory measures on national COVID-19 vaccination programs: a qualitative study from six EU member states. [PDF]

J Pharm Policy Pract
van Vliet ED, Buhl C, Jacobsen R, Andersen A, Almarsdóttir AB, Dermiki-Gkana F, Oikonomou C, Deligianni E, Kontogiorgis C, Kos M, Čebron Lipovec N, Ribeiro-Vaz I, Silva AM, Ferreira P, Poplavska E, Abtahi S, Hegger I, Leonardo Alves T.   +17 more
europepmc   +1 more source