Results 51 to 60 of about 132,336 (305)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

International Responsibility of the EU and/or its Member States in International Agreements: From Joint Participation to ‘Participation

open access: yes, 2022
The EU and its Member States’ participation in international agreements can be approached from two angles. A formal angle (participation ‘stricto sensu’) is linked to the division of competences to conclude international agreements, whereas the other ...
Andres Delgado Casteleiro   +1 more
core  

Foreign policies of EU member states: continuity and europeanisation

open access: yes, 2017
Foreign Policies of EU Member States provides a clear and current overview of the motivations and outcomes of EU Member States regarding their foreign policy-making within and beyond the EU.

core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Financial Convergence in the New EU Member States [PDF]

open access: yes
In this paper we explore the issue of financial convergence in the new EU member states (NMS). For the purposes of our analysis the countries falling into the category NMS are Bulgaria, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania,
Kalin Hristov, Rossen Rozenov
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

ENVIRONMENTAL LIABILITY OF EU MEMBER STATES

open access: yesPravo, 2011
The framework for the system of Environmental Liability of EU Member States is primarly established by Directive 2004/35/CE of the European Parliament and of the Council on environmental liability with regard to the prevention and remedying of ...
Jelena Matijašević, Marijana Alavuk
doaj  

THE TWOFOLD (INTERNAL AND EXTERNAL) DIMENSION OF EUROPEAN UNION’S MIGRATION AND ASYLUM POLICIES: RECENT CASES AND FUTURE SCENARIOS [PDF]

open access: yesEURINT, 2018
European Union’s policies on migration and asylum raise double-ditched problems. In the EU, the latter’s Court stated that in these areas solidarity is a binding principle: consequently, EU Member States must comply with EU decisions assigning quotas of ...
Alfredo RIZZO
doaj  

Home - About - Disclaimer - Privacy