Results 171 to 180 of about 556,266 (299)

Safety of the extension of use of oleoresin from <i>Haematococcus pluvialis</i> containing astaxanthin as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Cubbada F, Aguilera-Gómez M, Frenzel T, Heinonen M, Marcon F, McArdle HJ, Moldeus P, Neuhäuser-Berthold M, Poulsen M, Maradona MP, Schlatter JR, Gelbmann W, Hirsch-Ernst KI.   +27 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Assessment of the feed additives menadione sodium bisulphite (3a710) and menadione nicotinamide bisulphite (3a711) (vitamin K₃) for all animal species for the renewal of their authorisation (DSM Nutritional Products Ltd, KH Boddin GmbH, Oxyvit Kimya San. Ve Tic. A.Ş., Orffa Additives BV, FNF Ingredients EU BV, ADM International SàRL). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Ørnsrud R, Galobart J, Manini P, Navarro-Villa A, Pizzo F, Vettori MV, Gkimprixi E.   +23 more
europepmc   +1 more source

Energy tax harmonization in EU: Time series and panel data evidence [PDF]

This paper searches statistical evidence of tax harmonization initiated and motivated by EU Commission since 1980. The purpose of energy tax harmonization is to reach more efficient use of energy among members and thereby to establish more competitive ...
Bilgili, Faik
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Safety of UV-treated oil from yellow mealworm (<i>Tenebrio molitor</i> larvae) as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Aguilera-Gómez M, Cubadda F, Frenzel T, Heinonen M, Marcon F, McArdle HJ, Moldeus P, Neuhäuser-Berthold M, Schlatter JR, Poulsen M, Prieto Maradona M, Siskos A, van Loveren H, Mendes V, Ververis E, Hirsch-Ernst KI.   +30 more
europepmc   +1 more source

A Gravity Model Approach to Estimating Prospective Trade Gains in the EU Accession and Associated Countries [PDF]

Examining the trade prospects for the new European Union (EU) member states and the EU associated partner countries is an important issue in the context of European eastward enlargement and greater economic integration with its immediate neighbours.
Eric Pentecost, Marie Stack
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Safety of algal meal from <i>Haematococcus pluvialis</i> containing astaxanthin as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Cubbada F, Aguilera-Gómez M, Frenzel T, Heinonen M, Marcon F, McArdle HJ, Moldeus P, Neuhäuser-Berthold M, Poulsen M, Maradona MP, Schlatter JR, Gelbmann W, Hirsch-Ernst KI.   +27 more
europepmc   +1 more source

Macroeconomic Shocks and the Fiscal Stance within the EU: A Panel Regression Analysis [PDF]

The recent global financial crisis has had a diverse effect on countries’ fiscal stance, especially throughout the EU. This paper examines the impact of macroeconomic shocks, including those to government revenues and expenditures, on EU countries ...
Dybczak, Kamil, Melecky, Martin
core   +1 more source