Results 81 to 90 of about 5,071 (176)

Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav   +4 more
wiley   +1 more source

Context‐dependent TREM2 signalling in myeloid cells: Molecular mechanisms and immunotherapeutic divergence in neurodegeneration and cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Divergent triggering receptor expressed on myeloid cells 2 (TREM2) signalling pathways instruct myeloid cell adaptation towards neuroprotective disease‐associated microglia (DAM)/lipid‐associated macrophage (LAM) or immunosuppressive tumour‐associated macrophage (TAM) phenotypes.
Yaqing Lv   +5 more
wiley   +1 more source

The effect of a single, early-life administration of a probiotic on piglet growth performance and faecal microbiota until weaning

open access: yesItalian Journal of Animal Science, 2021
The establishment and maintenance of a balanced gut microbiota in early life play a pivotal role in pigs. This study aims to evaluate the effect of the administration of a single early-life probiotic on piglet faecal microbiota and growth performance ...
Diana Luise   +5 more
doaj   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, Volume 4, Issue 4, Page 824-859, October 2026.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Draft Genome Sequence of Lactobacillus rhamnosus NRRL B-442, a Potential Probiotic Strain

open access: yes, 2018
Lactic acid bacteria are known to exhibit probiotic properties through various mechanisms, including competitive exclusion, pathogen inhibition, production of antimicrobial substances, and maintenance of eubiosis.
Fahad H. Alqahtani   +3 more
core   +1 more source

Oral microbiome: Physiological and pathological impact on oral and systemic health [PDF]

open access: yesMedicinski Podmladak
The oral microbiome represents a complex and dynamic ecosystem of diverse microbial communities, whose variability arises from the specific anatomical and physiological conditions of the oral cavity.
Jovanović-Medojević Milica   +1 more
doaj   +1 more source

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

open access: yesVIEW, Volume 7, Issue 5, October 2026.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin   +5 more
wiley   +1 more source

Functions of intestinal microflora in children.

open access: yes, 2013
PURPOSE OF REVIEW: This review discusses the structural composition of intestinal microbiota, the functional relationship between the latter and the host, and the role of abnormal microflora in chronic diseases.
BUCCIGROSSI, VITTORIA   +2 more
core   +1 more source

Effects of GLP‐1 agonists on the gut microbiota in type 2 diabetes mellitus: a systematic review

open access: yesThe FEBS Journal, Volume 293, Issue 20, Page 5971-5995, October 2026.
This systematic review evaluated 17 studies (12 preclinical and five clinical) on GLP‐1 receptor agonists in type 2 diabetes, demonstrating effects on the gut microbiota and metabolic improvement. The studies showed an increase in Bacteroidetes, Lactobacillus, and Akkermansia, and a reduction in Firmicutes.
Ranicleide Santos Dantas   +11 more
wiley   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie   +12 more
wiley   +1 more source

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