Results 101 to 110 of about 5,276 (141)

Gold Nanoparticles Coated With the Antimicrobial Peptide Os‐C(W5): Anticandidal and Biological Activity

Journal of Peptide Science, Volume 32, Issue 9, September 2026.
Gold nanoparticles conjugated with a tick‐derived antimicrobial peptide, Os‐C(W5), demonstrate enhanced proteolytic stability and potent antifungal activity against Candida albicans biofilms and planktonic cells. These non‐cytotoxic nanoconjugates represent a promising biocompatible strategy for combating resistant fungal infections while maintaining ...
P. J. Palm, R. R. Chirombo, C. K. Chiramba, J. C. Serem, H. Taute, M. van der Walt, A. R. M. Gaspar, M. J. Bester   +7 more
wiley   +1 more source

Integrating CRRT as a Virtual Organ Into Physiologically Based Pharmacokinetic Modeling to Optimize Antimicrobial Dosing in Septic Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
Development and application of PBPK modeling integrating CRRT as a virtual organ to characterize antimicrobial pharmacokinetics and optimize dosing in septic patients. ABSTRACT Continuous renal replacement therapy (CRRT) extracorporeal drug removal, sepsis‐related pathophysiological alterations, and reduced pathogen susceptibility to antimicrobials can
Yuanming Xing, Yijing Zhang, Chuqi Bai, Yulan Qiu, Chuhui Wang, Lei Chen, Taotao Wang, Jiaojiao Chen   +7 more
wiley   +1 more source

mcr‐Mediated Colistin Resistance in Escherichia coli: A One Health Review of Reported Prevalence Across Human, Animal, Food, and Environmental Sectors

Public Health Challenges, Volume 5, Issue 3, September 2026.
This One Health review maps the global prevalence of mcr‐mediated colistin resistance in Escherichia coli across human, animal, food, and environmental sectors. By tracking datasets across diverse geographic regions, the study highlights critical resistance hotspots, emphasizing the urgent need for integrated cross‐sectoral surveillance to limit global
Ferdous‐Ul‐Haque Joy, Tashfiya Zaman Mouree, Munny Das, Asma Kabir   +3 more
wiley   +1 more source

Identification of Potential Vaccine Strains of Escherichia coli Isolates From Diarrhoeic Calves

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study aimed to identify vaccine candidate Escherichia coli strains isolated from diarrheic calves. Faecal samples collected from 500 calves were analysed, and E. coli strains were isolated and characterized phenotypically and genotypically. Antibiotic resistance profiles, virulence‐associated genes and MLVA genotyping were used to select 20 ...
Yasemin Erdoğan, Ediz Kağan Özgen, Murat Özmen, Elif Karadeniz Pütür, Nebahat Polat, Ersan Pütür, Mücahit Harmancı, Ercan Atalay, Ahmet Temur, Meryem Güloğlu, Lütfullah Celep, Seyda Cengiz, Mehmet Cemal Adıgüzel, Cihan Öz, Timur Gülhan, Alper Çiftci, Erhan Çiftgül   +16 more
wiley   +1 more source

Antibacterial Effect of the In Vitro Interaction Between Clotrimazole and Chlorhexidine Against Staphylococcus pseudintermedius With Known Resistance Patterns Isolated From Canine Pyoderma

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The 2:1 chlorhexidine–clotrimazole combination demonstrated enhanced antibacterial activity against canine Staphylococcus pseudintermedius isolates, including resistant strains. Reduced MIC values, predominantly additive interactions and absence of antagonism support its use as a promising topical strategy for canine pyoderma management.
Brenda Gallegos‐Torres, Edgar Alfonseca‐Silva, Claudia Ledesma‐Carrasco, Itzcoatl Aquino‐Díaz   +3 more
wiley   +1 more source

Nasal Colonization of Antimicrobial‐Resistant and Biofilm‐Producing Staphylococcus spp. in Surgical Canine Patients From Italy

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nasal Staphylococci in Surgical Canine Patients This study highlights a high occurrence of multidrug‐resistant (MDR) staphylococci isolated from nasal swabs of canine surgical patients, with Staphylococcus pseudintermedius being the most frequent pathogen.
Francesca Paola Nocera, Rossana Schena, Annunziata Romano, Stefano Cavalli, Laura Cortese, Gerardo Fatone, Luisa De Martino   +6 more
wiley   +1 more source

Changes in the interpretation of the results of susceptibility testing of fungi

Zdravniški Vestnik, 2014
The incidence of fungal infections is increasing together with the growing number of immunocompromised patients. For successful treatment it is necessary to select the optimal dose of a specific antifungal agent based on the in vitrosusceptibility ...
Rok Tomazin, Tadeja Matos
doaj  

A Four‐Center Study on the Activity of Aztreonam and Aztreonam‐Avibactam Combination Against Clinical Isolates of Gram‐Negative Bacilli Producing Representatives of Ambler Class A, B, C or D β‐Lactamases

APMIS, Volume 134, Issue 9, September 2026.
ABSTRACT We aimed to investigate the activity of aztreonam and aztreonam‐avibactam combination against gram‐negative bacilli producing different types of β‐lactamases. Activity of aztreonam and aztreonam‐avibactam against 166 isolates (33 AmpC‐producing, 33 ESBL‐producing, 66 carbapenemase‐producing Enterobacterales, 34 metallo‐β‐lactamase‐producing P.
Gizem İnce Ceviz, Hasan Cenk Mirza, Aylin Üsküdar Güçlü, Özlem Öğüç Şanlı, Özlem Kurt Azap, Banu Sancak, Elvan Hortaç İştar, Ahmet Başustaoğlu   +7 more
wiley   +1 more source

Antifungal susceptibility and molecular characterization of clinical and environmental isolates of Schizophyllum commune

Journal of Clinical Microbiology
Schizophyllum commune is a cosmopolitan, saprophytic basidiomycete known to cause respiratory tract infections following spore inhalation. Management of such infections remained poorly defined, and antifungal susceptibility testing may provide valuable ...
Grégoire Pasquier, Pierre-Olivier Harmand, Laura Le Feur, Emilie Guemas, Anne Pauline Bellanger, Danièle Maubon, Anne Favel, Claire Cottrel, Lilia Hasseine, Marcela Sabou, Eric Dannaoui, Arnaud Fekkar, Anne-Cécile Normand, Jean-Pierre Gangneux, Laurence Delhaes, Milène Sasso, Laurence Lachaud   +16 more
doaj   +1 more source

Posaconazole Target Attainment in Critically Ill Children: A 15‐Year Single‐Center Retrospective Analysis

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Posaconazole is a triazole antifungal agent used for prophylaxis and treatment of invasive fungal diseases. Posaconazole has high inter‐individual variability in dose‐exposure relationship and benefits from therapeutic drug monitoring (TDM). Adult studies report particularly high rates of subtherapeutic exposure among intensive care unit (ICU)
Kathryn Pavia, Addison Pritchett, Jennifer Goldman   +2 more
wiley   +1 more source