Results 111 to 120 of about 25,547 (271)

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source

Pefloxacin as a Surrogate Marker for Fluoroquinolone Susceptibility for Salmonella typhi: Problems and Prospects [PDF]

Journal of Clinical and Diagnostic Research, 2016
Balaji Veeraraghavan, Shalini Anandan, Dhiviya Prabaa Muthuirulandi Sethuvel, Naveen Kumar Devanga Ragupathi   +3 more
doaj   +1 more source

Universal‐Bac3Gel: A 3D Biofilm‐Relevant Matrix That Supports In Vitro Growth and Biofilm Formation of ESKAPE Pathogens

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Universal‐Bac3Gel, a 3D biofilm‐relevant matrix with oxygen and nutrient gradients, supports the growth and species‐specific biofilm architectures of all ESKAPE pathogens, offering a physiologically relevant platform for antimicrobial testing and microbiological research. ABSTRACT Human microbiota is increasingly considered to shape health and disease,
Emanuela Peluso, Sebastião van Uden, Sonja Visentin, Paola Petrini, Daniela Peneda Pacheco, Livia Visai   +5 more
wiley   +1 more source

Estimating the Breakpoints for EUCAST Fast Antimicrobial Susceptibility Testing Using Flagged BacT/Alert Blood Culture Bottles

Online Journal of Health & Allied Sciences
Introduction: The escalating prevalence of multidrug resistance is a global threat to human health particularly in critically ill patients with bloodstream infections (BSIs).
Seema Gangar, Kirti Nirmal, Avinash Kant Lakra, Kalyani Swain, Shukla Das   +4 more
doaj  

HB&L System: rapid determination of antibiotic sensitivity of bacteria isolated from blood cultures.

Microbiologia Medica, 2010
Introduction. Blood culture is an important method to detect microbial pathogens on blood, very useful for diagnosing bacterial infections. Unfortunately, classical diagnostic protocols cannot directly identify bacteria responsible for sepsis and ...
Simone Barocci, Marinella Giacomini, Antonella Renzi, Marcello Palma, Luciano Latini, Luciano Quagliarini, Antonio Migali   +6 more
doaj   +1 more source

Longitudinal Molecular Epidemiology and Genomic Surveillance of Carbapenem‐Resistant Klebsiella pneumoniae in the Gut of Healthy Individuals in China

MedComm, Volume 7, Issue 8, August 2026.
Using 16,040 stool samples from healthy individuals across 30 Chinese provinces (2016–2024), we performed longitudinal genomic surveillance of carbapenem‑resistant Klebsiella pneumoniae (CRKP) colonizing the gut. We reveal rising community CRKP prevalence, especially in southern China, a shift from blaKPC‐2 to plasmid‑borne blaNDM‐5 on IncHI2/IncHI2A ...
Zelin Yan, Yan Li, Yi Sun, Qiaoling Sun, Congcong Liu, Yanyan Zhang, Yuchen Wu, Hongwei Zhou, Shangshang Qin, Gongxiang Chen, Ruichao Li, Rong Zhang   +11 more
wiley   +1 more source

Antimicrobial Stewardship Strategies for Implementing the 2019 EUCAST ‘I’ Definition

BMC Infectious Diseases
Abstract Background In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) redefined the “I” category from “intermediate susceptibility” to “susceptible, provided increased exposure”.
Evelyne Van den Broucke, Charlotte Quintens, Willy E. Peetermans, Eric Van Wijngaerden, Otto Van de gaer, Stefanie Desmet, Isabel Spriet   +6 more
openaire   +3 more sources

Prediction of Antimicrobial Resistance in People Living With Cystic Fibrosis Using Machine Learning

MedComm, Volume 7, Issue 8, August 2026.
Using routinely collected electronic healthcare record data from patients with cystic fibrosis, machine learning models predicted antimicrobial resistance in sputum cultures before susceptibility results were available. Extreme gradient boosting showed consistent discrimination across five commonly tested antibiotics, with AUCs of 0.75–0.80.
Junrong Jiang, Akhil Naik, Dilip Nazareth, Dennis Wat, Graham Hyde, Jo Fothergill, Sarah Benabidallah, Gregory Y. H. Lip, Sandra Ortega‐Martorell, Ivan Olier, Freddy Frost   +10 more
wiley   +1 more source

EUCAST Technical Note on tigecycline [PDF]

Clinical Microbiology and Infection, 2006
Brown, D.F.J., Canton, R., MacGowan, A.P., Mouton, J.W., Rodloff, A., Goldstein, F., Odenholt, I., Steinbakk, M., Varaldo, P., Hryniewicz, W., The European Committee on Antimicrobial Susceptibility Testing (EUCAST) Steering Committee, , Kahlmeter, G.   +11 more
openaire   +2 more sources