Results 91 to 100 of about 15,818 (212)

Subcellular organization of UBE3A in human cerebral cortex

open access: yesMolecular Autism, 2018
Background Loss of UBE3A causes Angelman syndrome, whereas excess UBE3A activity appears to increase the risk for autism. Despite this powerful association with neurodevelopmental disorders, there is still much to be learned about UBE3A, including its ...
Alain C. Burette   +6 more
doaj   +1 more source

Feulgen-DNA absorption spectrum of euchromatin and constitutive heterochromatin. [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1978
When the heterochromatin and euchromatin of Triatoma infestans are maximally depurinated, their Feulgen-DNA spectral profiles exhibit a shoulder at about lambda = 530 nm. The shoulder is especially prominent in the curves of the heterochromatin. It is assumed that this pattern is related to richness in repetitive DNA in the heterochromatin, favoring ...
openaire   +3 more sources

Fluctuations in DNA Packing Density Drive the Spatial Segregation between Euchromatin and Heterochromatin [PDF]

open access: yesarXiv
In the crowded eukaryotic nucleus, euchromatin and heterochromatin segregate into distinct compartments, a phenomenon often attributed to homotypic interactions mediated by liquid liquid phase separation of chromatin associated proteins. Here, we revisit genome compartmentalization by examining the role of in vivo DNA packing density fluctuations ...
arxiv  

Structural basis of thymidine-rich DNA recognition by Drosophila P75 PWWP domain

open access: yesCommunications Biology
Drosophila P75 (dP75), a homolog of the human LEDGF/p75, is crucial for oogenesis by recruiting the histone kinase Jil-1 to euchromatin and impeding H3K9me2 spreading.
Zhaohui Jin   +8 more
doaj   +1 more source

Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions

open access: yesBMC Genomics, 2012
Background The organization of higher order chromatin is an emerging epigenetic mechanism for understanding development and disease. We and others have previously observed dynamic changes during differentiation and oncogenesis in large heterochromatin ...
Wen Bo   +5 more
doaj   +1 more source

Highly Specific Antibodies Determine Histone Acetylation Site Usage in Yeast Heterochromatin and Euchromatin [PDF]

open access: bronze, 2001
Noriyuki Suka   +4 more
openalex   +1 more source

Home - About - Disclaimer - Privacy