Results 11 to 20 of about 15,818 (212)
Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast
Biomolecules, 2023 DNA is stored in the nucleus of a cell in a folded state; however, only the necessary genetic information is extracted from the required group of genes. The key to extracting genetic information is chromatin ambivalence.
Shinya Takahata, Yota Murakami
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gammaH2AX foci form preferentially in euchromatin after ionising-radiation.
PLoS ONE, 2007 BackgroundThe histone variant histone H2A.X comprises up to 25% of the H2A complement in mammalian cells. It is rapidly phosphorylated following exposure of cells to double-strand break (DSB) inducing agents such as ionising radiation.
Ian G Cowell +5 more
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Nuclear dynamical deformation induced hetero- and euchromatin positioning [PDF]
Physical Review E, 2015 The contributions of active deformation dynamics in cell nuclei to the intra-nuclear positioning of hetero- and euchromatin are investigated. We analyzed the behaviors of model chains containing two types of regions, one with high and the other with low mobility, confined in a pulsating container.
arxiv +6 more sources
Active Hydrodynamic Theory of Euchromatin and Heterochromatin [PDF]
arXivThe genome contains genetic information essential for cell's life. The genome's spatial organization inside the cell nucleus is critical for its proper function including gene regulation. The two major genomic compartments -- euchromatin and heterochromatin -- contain largely transcriptionally active and silenced genes, respectively, and exhibit ...
Rautu, S. Alex +3 more
arxiv +3 more sources
Replication of the Mammalian Genome by Replisomes Specific for Euchromatin and Heterochromatin [PDF]
Frontiers in Cell and Developmental Biology, 2021 Replisomes follow a schedule in which replication of DNA in euchromatin is early in S phase while sequences in heterochromatin replicate late. Impediments to DNA replication, referred to as replication stress, can stall replication forks triggering activation of the ATR kinase and downstream pathways.
Jing Zhang +8 more
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A physical model of euchromatin organization. [PDF]
Proc Natl Acad Sci U S ALequieu J.
europepmc +3 more sources
Euchromatin and Pericentromeric Heterochromatin: Comparative Composition in the Tomato Genome [PDF]
Genetics, 2006 Abstract Eleven sequenced BACs were annotated and localized via FISH to tomato pachytene chromosomes providing the first global insights into the compositional differences of euchromatin and pericentromeric heterochromatin in this model dicot species.
Ying Wang +5 more
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Molecular Complexes at Euchromatin, Heterochromatin and Centromeric Chromatin [PDF]
International Journal of Molecular Sciences, 2021 Chromatin consists of a complex of DNA and histone proteins as its core components and plays an important role in both packaging DNA and regulating DNA metabolic pathways such as DNA replication, transcription, recombination, and chromosome segregation. Proper functioning of chromatin further involves a network of interactions among molecular complexes
Jitendra K. Thakur, Olivia Morrison
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Targeted Inter-Homologs Recombination in Arabidopsis Euchromatin and Heterochromatin [PDF]
International Journal of Molecular Sciences, 2021 Homologous recombination (HR) typically occurs during meiosis between homologs, at a few unplanned locations along the chromosomes. In this study, we tested whether targeted recombination between homologous chromosomes can be achieved via Clustered Regulatory Interspaced Short Palindromic Repeat associated protein Cas9 (CRISPR-Cas9)-induced DNA double ...
Shdema Filler-Hayut +3 more
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Current Analytical Strategies in Studying Chromatin-Associated-Proteome (Chromatome)
Molecules, 2021 Chromatin is a dynamic structure comprising of DNA and proteins. Its unique nature not only help to pack the DNA tightly within the cell but also is pivotal in regulating gene expression DNA replication.
Niamat Khan, Sidra Shahid, Abdul R. Asif
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