Results 11 to 20 of about 16,530 (161)
Super-Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation. [PDF]
Adv Sci (Weinh)A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Pabba MK +11 more
europepmc +2 more sources
A Liquid State Perspective on Dynamics of Chromatin Compartments
Frontiers in Molecular Biosciences, 2022 The interior of the eukaryotic cell nucleus has a crowded and heterogeneous environment packed with chromatin polymers, regulatory proteins, and RNA molecules.
Rabia Laghmach +2 more
doaj +1 more source
The hierarchical packing of euchromatin domains can be described as multiplicative cascades.
PLoS Computational Biology, 2021 The genome is packed into the cell nucleus in the form of chromatin. Biochemical approaches have revealed that chromatin is packed within domains, which group into larger domains, and so forth.
Amra Noa +4 more
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Protocol for detecting chromatin dynamics and screening chromatin relaxer by FRAP assay
STAR Protocols, 2021 Summary: We describe a fluorescence recovery after photobleaching (FRAP) protocol for assessing the dynamics of heterochromatin/euchromatin and identifying chromatin relaxers for cell fate transition.
Qi Long +6 more
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The FUN30 chromatin remodeler, Fft3, protects centromeric and subtelomeric domains from euchromatin formation. [PDF]
PLoS Genetics, 2011 The chromosomes of eukaryotes are organized into structurally and functionally discrete domains. This implies the presence of insulator elements that separate adjacent domains, allowing them to maintain different chromatin structures.
Annelie Strålfors +3 more
doaj +1 more source
Development of Artificial System to Induce Chromatin Loosening in Saccharomyces cerevisiae
Biomolecules, 2022 In eukaryotic cells, loosening of chromatin causes changes in transcription and DNA replication. The artificial conversion of tightly packed chromatin (heterochromatin) to loosely packed chromatin (euchromatin) enables gene expression and regulates cell ...
Ryota Yamamoto +4 more
doaj +1 more source
Scientific Reports, 2021 A characteristic spatial distribution of the main chromatin fractions is observed in most mammalian cell nuclei, with euchromatin localized in the interior and heterochromatin at the nuclear periphery.
Joanna Stachecka +3 more
doaj +1 more source
mBio, 2019 Eukaryotic genomes are packaged into chromatin structures that play pivotal roles in regulating all DNA-associated processes. Histone posttranslational modifications modulate chromatin structure and function, leading to rapid regulation of gene ...
Robert Jordan Price +3 more
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Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin. [PDF]
PLoS ONE, 2011 H2Av is a versatile histone variant that plays both positive and negative roles in transcription, DNA repair, and chromatin structure in Drosophila.
Zhenhai Zhang, B Franklin Pugh
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European Journal of Entomology, 2014 The occurrence of transposable elements (TEs) is a ubiquitous characteristic of eukaryotic genomes, and these sequences are highly abundant in some species. Due to their large genomes, grasshoppers (Orthoptera) appear to be potentially good candidates in
Octavio M. PALACIOS-GIMENEZ +2 more
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