The Chromatin of Candida albicans Pericentromeres Bears Features of Both Euchromatin and Heterochromatin [PDF]
Frontiers in Microbiology, 2016 Centromeres, sites of kinetochore assembly, are important for chromosome stability and integrity. Most eukaryotes have regional centromeres epigenetically specified by the presence of the histone H3 variant CENP-A. CENP-A chromatin is often surrounded by
Verónica Freire-Benéitez +2 more
semanticscholar +7 more sources
Molecular Complexes at Euchromatin, Heterochromatin and Centromeric Chromatin [PDF]
International Journal of Molecular Sciences, 2021 Chromatin consists of a complex of DNA and histone proteins as its core components and plays an important role in both packaging DNA and regulating DNA metabolic pathways such as DNA replication, transcription, recombination, and chromosome segregation ...
Olivia Morrison, J. Thakur
semanticscholar +4 more sources
Targeted Inter-Homologs Recombination in Arabidopsis Euchromatin and Heterochromatin [PDF]
International Journal of Molecular Sciences, 2021 Homologous recombination (HR) typically occurs during meiosis between homologs, at a few unplanned locations along the chromosomes. In this study, we tested whether targeted recombination between homologous chromosomes can be achieved via Clustered ...
Shdema Filler-Hayut +3 more
semanticscholar +4 more sources
Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast
Biomolecules, 2023 DNA is stored in the nucleus of a cell in a folded state; however, only the necessary genetic information is extracted from the required group of genes. The key to extracting genetic information is chromatin ambivalence.
Shinya Takahata, Yota Murakami
doaj +3 more sources
gammaH2AX foci form preferentially in euchromatin after ionising-radiation.
PLoS ONE, 2007 BackgroundThe histone variant histone H2A.X comprises up to 25% of the H2A complement in mammalian cells. It is rapidly phosphorylated following exposure of cells to double-strand break (DSB) inducing agents such as ionising radiation.
Ian G Cowell +5 more
doaj +5 more sources
Translocation Breakpoints Preferentially Occur in Euchromatin and Acrocentric Chromosomes [PDF]
Cancers, 2018 Chromosomal translocations drive the development of many hematological and some solid cancers. Several factors have been identified to explain the non-random occurrence of translocation breakpoints in the genome.
Cheng-Yu Lin +5 more
semanticscholar +6 more sources
Differential DNA lesion formation and repair in heterochromatin and euchromatin. [PDF]
Carcinogenesis, 2016 Discretely orchestrated chromatin condensation is important for chromosome protection from DNA damage. However, it is still unclear how different chromatin states affect the formation and repair of nucleotide excision repair (NER) substrates, e.g ...
Chunhua Han +4 more
semanticscholar +4 more sources
Nuclear dynamical deformation induced hetero- and euchromatin positioning. [PDF]
Physical Review E, 2015 We studied the role of active deformation dynamics in cell nuclei in chromatin positioning. Model chains containing two types of regions, with high (euchromatic) or low (heterochromatic) mobility, were confined in a pulsating container simulating a ...
A. Awazu
semanticscholar +5 more sources
Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair [PDF]
Nature CommunicationsDNA double-strand breaks (DSBs) must be properly repaired within diverse chromatin domains to maintain genome stability. Whereas euchromatin has an open structure and is associated with transcription, facultative heterochromatin is essential to silence ...
Marieke R. Wensveen +7 more
doaj +2 more sources
The Ino80 complex prevents invasion of euchromatin into silent chromatin [PDF]
Genes & Development, 2015 Xue et al. show that the Ino80 chromatin remodeling complex (Ino80C) directly prevents euchromatin from invading transcriptionally silent chromatin within intergenic regions and at the border of euchromatin and heterochromatin.
Yong Xue +12 more
semanticscholar +7 more sources